Mayzent (Siponimod)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Mayzent Used For?
Mayzent is a medication that helps manage symptoms of multiple sclerosis, particularly in adults with secondary progressive multiple sclerosis (SPMS).
Primary Uses
Mayzent is primarily used to treat secondary progressive multiple sclerosis (SPMS) in adults.
How It Works
Mayzent works by slowing down the progression of multiple sclerosis, reducing disability and nerve damage associated with the condition.
Good to know: Mayzent is not considered addictive.
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How to Take Mayzent
Follow the prescribed dosage and instructions for taking Mayzent to ensure effective treatment.
Dosage Instructions
Begin treatment with a starter titration pack for 5 days, followed by a usual dose of one 2mg tablet taken once daily. For some patients with specific genotypes, the usual dose may be 1mg once daily.
What If You Miss a Dose?
If you miss a dose, take it as soon as you remember. If it's close to your next dose, skip the missed dose. Do not take a double dose. If you miss a dose during the first 6 days of treatment, contact your doctor for a new starter titration pack.
Important: Never double dose to make up for a missed dose.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- headache
- dizziness
- diarrhoea
- feeling unwell
- pain in arms or legs
- weakness
- shaking
Seek immediate medical attention if you experience:
- infections (e.g., shingles)
- slow or irregular heartbeat
- skin cancer (e.g., basal cell carcinoma)
- worsening multiple sclerosis symptoms
- difficulty breathing
- convulsions
Important Warnings
It's crucial to be aware of certain warnings before using Mayzent.
Who Should Not Take Mayzent
Do not use Mayzent if you have had an allergic reaction to it or its ingredients, have certain heart conditions, or have the CYP2C9 *3*3 genotype.
Medical Conditions to Discuss
Discuss with your doctor if you have infections, liver problems, uncontrolled high blood pressure, or are planning to receive vaccines.
Pregnancy and Breastfeeding
Avoid using Mayzent while pregnant or breastfeeding. Discuss effective birth control options with your doctor.
Drug Interactions
Certain medications may interact with Mayzent, affecting its effectiveness.
- Medicines for irregular heartbeat (e.g., quinidine, procainamide)
- Medicines that slow down heartbeat (e.g., verapamil, diltiazem)
- Immunosuppressive medications
- Live attenuated vaccines
- Carbamazepine
- Modafinil
- Fluconazole
Alcohol & Driving
Be cautious with alcohol consumption and operating machinery while taking Mayzent.
Alcohol
There are no known interactions between Mayzent and alcohol.
Driving and Operating Machinery
Mayzent may cause dizziness; use caution until you know how it affects you.
Storage
Store Mayzent in the refrigerator between 2°C and 8°C. After opening, 1mg and 2mg tablets can be stored below 30°C for up to 3 months.
Overdose Information
If you suspect an overdose, seek immediate medical attention. Contact the Poisons Information Centre at 13 11 26 or go to the nearest hospital.
Frequently Asked Questions
The effects of Mayzent may vary, but it is designed to slow the progression of multiple sclerosis over time.
You can take Mayzent with or without food.
No, Mayzent is not considered addictive.
Stopping Mayzent suddenly can lead to a return of multiple sclerosis symptoms, which may worsen.
There are no known interactions between Mayzent and alcohol, but use caution.
Weight gain is not listed as a common side effect of Mayzent.
Consult your doctor for guidance on the safety of Mayzent for elderly patients.
Take the missed dose as soon as you remember, but skip it if it's close to your next dose.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.