Inflectra (Infliximab)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Inflectra Used For?
Inflectra is a biosimilar medication that contains infliximab, used to treat various autoimmune conditions.
Primary Uses
Inflectra is primarily used for rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, moderate to severe psoriasis, Crohn's disease, and ulcerative colitis.
How It Works
Inflectra works by blocking tumor necrosis factor alpha (TNFα), a protein that contributes to inflammation in autoimmune diseases.
Good to know: Inflectra is not addictive.
Continue Reading
Sign in to access the complete medication guide including dosage, side effects, warnings, and more.
How to Take Inflectra
Inflectra is given as an infusion into a vein, typically over a period of at least 2 hours.
Dosage Instructions
The starting dose for rheumatoid arthritis is 3 mg/kg, for ankylosing spondylitis and psoriasis is 5 mg/kg, and for Crohn's disease and ulcerative colitis is also 5 mg/kg. Doses are repeated at specified intervals.
What If You Miss a Dose?
If you miss an appointment for your infusion, reschedule as soon as possible. Your doctor will determine the next appropriate dose.
Important: Never double the dose if you miss an appointment.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- fever
- headache
- dizziness
- nausea
- diarrhea
- rash
Seek immediate medical attention if you experience:
- severe infections
- allergic reactions
- heart failure symptoms
- liver problems
- new or worsening autoimmune conditions
Impulse Control Issues
No specific information about impulse control issues was mentioned.
Important Warnings
There are several important considerations before using Inflectra.
Who Should Not Take Inflectra
Do not use Inflectra if you have a history of allergic reactions to mouse proteins, severe infections, or if you are taking anakinra.
Medical Conditions to Discuss
Discuss any history of infections, congestive heart failure, or cancer with your doctor before starting Inflectra.
Pregnancy and Breastfeeding
Inflectra is not recommended during pregnancy as it can cross the placenta. It is also present in breast milk, so consult your doctor if breastfeeding.
Elderly Patients With Dementia: Special caution is advised for elderly patients, particularly those with dementia.
Drug Interactions
Certain medications may interact with Inflectra.
Grapefruit interaction: No specific grapefruit interaction mentioned.
- anakinra
- abatacept
- other treatments for rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, psoriasis, Crohn’s disease, or ulcerative colitis
Alcohol & Driving
Inflectra is unlikely to cause drowsiness, but if you feel tired, avoid driving or operating machinery.
Alcohol
Consult your doctor regarding alcohol consumption while on Inflectra.
Driving and Operating Machinery
Do not drive or operate machinery if you feel fatigued.
Temperature Regulation
No specific temperature regulation warnings mentioned.
Storage
Store Inflectra as directed by your healthcare provider, typically in a cool, dry place.
Overdose Information
Overdose is unlikely as Inflectra is administered under medical supervision. If overdose is suspected, seek immediate medical attention.
Frequently Asked Questions
Inflectra may take several weeks to show its full effect.
Inflectra is administered via infusion, so food does not affect its intake.
No, Inflectra is not considered addictive.
Consult your doctor before stopping Inflectra to discuss potential effects.
Consult your doctor regarding alcohol consumption while on Inflectra.
Weight changes are not specifically mentioned as a side effect of Inflectra.
Elderly patients should use Inflectra with caution, especially those with dementia.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.