Glivec Tablets (Imatinib)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
imatinib
Drug Class
tyrosine kinase inhibitors
Used For
treating certain types of cancer and leukemia
How Taken
oral tablet, usually once daily with food

What Is Glivec Tablets Used For?

Glivec contains imatinib and is used to treat specific cancers and leukemias in both children and adults.

Primary Uses

Glivec is used to treat chronic myeloid leukaemia (CML), acute lymphoblastic leukaemia with Philadelphia chromosome positive (Ph-positive ALL), myelodysplastic/myeloproliferative diseases (MDS/MPD), aggressive systemic mastocytosis (ASM), hypereosinophilic syndrome (HES), chronic eosinophilic leukaemia (CEL), gastrointestinal stromal tumours (GIST), and dermatofibrosarcoma protuberans (DFSP).

How It Works

Glivec works by slowing the growth of cancer cells while sparing normal cells.

Good to know: Glivec is not considered addictive.

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How to Take Glivec Tablets

Follow your doctor's instructions on how to take Glivec.

Dosage Instructions

Your doctor will specify the exact number of tablets to take. Glivec is typically taken as a single daily dose, but your doctor may recommend splitting it into two doses.

What If You Miss a Dose?

If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose.

Important: Never double the dose to make up for a missed one.

Available Tablet Strengths

100mg
100mg Tablet Dark yellow to brownish orange, Round • NVR
400mg
400mg Tablet Dark yellow to brownish orange, Oval • 400

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • headache
  • dizziness
  • nausea
  • vomiting
  • diarrhoea
  • constipation
  • skin rash
  • itchy or dry skin
  • fatigue
  • hair loss

Seek immediate medical attention if you experience:

  • unexpected bleeding or bruising
  • severe stomach pain
  • dark urine
  • yellow skin or eyes
  • chest pain
  • irregular heartbeat
  • severe headache
  • muscle weakness or spasms

Important Warnings

Be aware of the following warnings before using Glivec.

Who Should Not Take Glivec Tablets

Do not use Glivec if you are allergic to imatinib or any of its ingredients.

Medical Conditions to Discuss

Inform your doctor if you have kidney or liver issues, heart problems, or if you've had your thyroid gland removed. Hepatitis B infection should also be discussed.

Pregnancy and Breastfeeding

Consult your doctor if you are pregnant or plan to become pregnant, as Glivec may harm an unborn baby. Breastfeeding is not recommended while taking Glivec.

Drug Interactions

Certain medications may interact with Glivec and affect its efficacy.

Grapefruit interaction: Avoid grapefruit juice while taking Glivec, as it may affect how the medication works.

  • St. John's wort
  • paracetamol
  • rifampicin
  • ketoconazole
  • erythromycin
  • clarithromycin
  • itraconazole
  • antiviral medicines for HIV/AIDS
  • dexamethasone
  • simvastatin
  • phenytoin
  • carbamazepine
  • phenobarbitone
  • warfarin
  • certain mental health medications
  • certain blood pressure medications
  • cyclosporin

Alcohol & Driving

Be cautious with alcohol consumption and operating machinery while on Glivec.

Alcohol

There are no known interactions between Glivec and alcohol, but consult your doctor if you drink.

Driving and Operating Machinery

Be careful when driving or using machines until you know how Glivec affects you, as it may cause dizziness.

Storage

Store Glivec in its original container in a cool, dry place away from moisture and sunlight. Keep out of reach of children.

Overdose Information

If you suspect an overdose, seek immediate medical attention. Contact the Poisons Information Centre at 13 11 26 or go to the nearest hospital.

Frequently Asked Questions

The time it takes for Glivec to work can vary by individual and condition; consult your doctor for specific expectations.

Yes, it is recommended to take Glivec with food to help avoid stomach irritation.

No, Glivec is not considered addictive.

Do not stop taking Glivec suddenly without consulting your doctor, as this could affect your treatment.

There are no known interactions between Glivec and alcohol, but it's best to consult your doctor.

Weight changes can occur; discuss any concerns with your doctor.

Elderly patients should consult their doctor to ensure Glivec is safe for their specific health conditions.

If you miss a dose, take it as soon as you remember, but skip it if it's almost time for your next dose. Do not double dose.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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