Eliquis (Apixaban)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Eliquis Used For?
Eliquis is a medication that contains the active ingredient apixaban, used to prevent and treat blood clots.
Primary Uses
Eliquis is used to prevent blood clots after hip or knee replacement surgery, treat deep vein thrombosis (DVT) and pulmonary embolism (PE), and prevent strokes in patients with atrial fibrillation.
How It Works
Eliquis works by inhibiting Factor Xa, a substance in the blood that helps clots form.
Good to know: Eliquis is not addictive.
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How to Take Eliquis
Follow your doctor's instructions on how to take Eliquis.
Dosage Instructions
For hip or knee replacement surgery, the recommended dose is one 2.5 mg tablet taken twice daily. For treating blood clots, the dose is two 5 mg tablets twice daily for 7 days, then one 5 mg tablet twice daily. For atrial fibrillation, the usual dose is one 5 mg tablet twice daily, or one 2.5 mg tablet twice daily if you are 80 years or older, weigh 60 kg or less, or have reduced kidney function.
What If You Miss a Dose?
If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue your regular schedule. Do not take a double dose.
Important: Never double the dose to make up for a missed dose.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- tiredness
- weakness
- dizziness
- nausea
- vomiting
- bruising
Seek immediate medical attention if you experience:
- excessive or prolonged bleeding
- allergic reactions (shortness of breath, swelling, rash)
- blood in urine or stools
- dark brown urine
Impulse Control Issues
There is no specific mention of impulse control issues related to Eliquis.
Important Warnings
There are several important warnings to consider before taking Eliquis.
Who Should Not Take Eliquis
Do not take Eliquis if you are allergic to apixaban or any of its ingredients, have active bleeding conditions, severe liver disease, or significantly reduced kidney function.
Medical Conditions to Discuss
Discuss with your doctor if you have a history of bleeding disorders, heart conditions, or if you are over 75 years old, as these may increase the risk of bleeding.
Pregnancy and Breastfeeding
Eliquis is not recommended for use during pregnancy or breastfeeding due to potential risks to the baby.
Elderly Patients With Dementia: Elderly patients may require closer monitoring due to increased bleeding risk.
Drug Interactions
Certain medications may interact with Eliquis and affect its effectiveness.
Grapefruit interaction: Grapefruit may affect how Eliquis works.
- medicines for fungal infections (e.g., ketoconazole, itraconazole)
- anti-viral medicines for HIV/AIDS (e.g., ritonavir)
- other anticoagulants (e.g., heparin, warfarin, rivaroxaban, dabigatran)
Alcohol & Driving
Be cautious with alcohol and driving while taking Eliquis.
Alcohol
Limit alcohol intake as it may increase the risk of bleeding.
Driving and Operating Machinery
Eliquis is not expected to impair your ability to drive, but be cautious and report any changes in your ability to your doctor.
Storage
Store Eliquis in a cool, dry place away from moisture, heat, and sunlight. Keep it in its original packaging until it's time to take it.
Overdose Information
If you suspect an overdose, seek immediate medical attention. Symptoms may include uncontrolled bleeding.
Frequently Asked Questions
Eliquis begins to work shortly after taking it, but the exact time can vary based on individual factors.
Eliquis can be taken with or without food.
No, Eliquis is not considered addictive.
Stopping Eliquis suddenly can increase the risk of blood clots, which may lead to serious complications.
It's advisable to limit alcohol consumption while taking Eliquis due to the increased risk of bleeding.
Elderly patients may require closer monitoring due to a higher risk of bleeding.
If you miss a dose, take it as soon as you remember, but do not double the dose.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.