Domion (Agomelatine)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
agomelatine
Drug Class
antidepressant
Used For
treatment of depression and anxiety, prevention of relapse
How Taken
oral tablet, usually at bedtime

What Is Domion Used For?

Domion is a medication that contains agomelatine, primarily used to treat depression and anxiety disorders.

Primary Uses

Domion is used for treating major depressive episodes and generalized anxiety disorder.

How It Works

Domion helps regulate the body's circadian rhythm, which can positively affect mood and sleep.

Good to know: Domion is not addictive and does not cause withdrawal symptoms when stopping.

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How to Take Domion

It is important to follow your doctor's instructions when taking Domion.

Dosage Instructions

The usual dose is one tablet at bedtime, with a maximum of two tablets (50 mg) daily if prescribed by your doctor.

What If You Miss a Dose?

If you miss a dose, skip it and take the next one at the usual time. Do not double up on doses.

Important: Never take more than the prescribed dose.

Available Tablet Strengths

5mg
5mg Tablet Blue, Round • A-007
10mg
10mg Tablet Pink, Rectangular • A-008
15mg
15mg Tablet Yellow, Round • A-009
20mg
20mg Tablet White, Round • A-010
30mg
30mg Tablet Pink, Round • A-011

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • nausea
  • diarrhea
  • constipation
  • headache
  • dizziness
  • sleepiness

Seek immediate medical attention if you experience:

  • severe liver reactions
  • severe allergic reactions
  • thoughts of self-harm or suicide

Impulse Control Issues

Some patients may experience increased agitation or impulsive behaviors.

Important Warnings

There are several important considerations before using Domion.

Who Should Not Take Domion

Do not use Domion if you are allergic to agomelatine, have liver disease, or are taking fluvoxamine or ciprofloxacin.

Medical Conditions to Discuss

Discuss any history of liver issues, bipolar disorder, or dementia with your doctor.

Pregnancy and Breastfeeding

Consult your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.

Elderly Patients With Dementia: Domion is not recommended for elderly patients with dementia.

Drug Interactions

Certain medications can interact with Domion.

  • fluvoxamine
  • ciprofloxacin
  • propranolol

Alcohol & Driving

Caution is advised regarding alcohol consumption and driving while taking Domion.

Alcohol

Avoid alcohol as it can worsen depression and may lead to liver problems.

Driving and Operating Machinery

Be cautious when driving or operating machinery until you know how Domion affects you.

Storage

Store Domion in a cool, dry place below 30°C, away from moisture and out of reach of children.

Overdose Information

If you suspect an overdose, seek immediate medical attention. Symptoms may include drowsiness, agitation, or abdominal pain.

Frequently Asked Questions

Some people may notice improvements within two to four weeks of starting treatment.

Domion can be taken with or without food.

No, Domion is not addictive and does not cause withdrawal symptoms.

You can stop taking Domion without tapering, as it does not cause discontinuation symptoms.

It is recommended to avoid alcohol while taking Domion.

Weight changes can occur, but specific effects vary by individual.

Domion is not recommended for elderly patients with dementia.

If you miss a dose, skip it and take the next dose at the usual time.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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