Lacosam (Lacosamide)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
lacosamide
Drug Class
antiepileptic
Used For
controlling epilepsy and seizures
How Taken
oral tablets taken twice daily

What Is Lacosam Used For?

Lacosam is an antiepileptic medication used to control seizures in people with epilepsy. It can be used alone in patients over 16 years or combined with other seizure medications.

Primary Uses

Lacosam is used to control epilepsy, a condition where you have repeated seizures. There are many different types of seizures, ranging from mild to severe. It’s not recommended for children under 4 years as safety and effectiveness haven’t been established in this age group.

How It Works

This medicine belongs to a group called antiepileptics. These medicines work by controlling brain chemicals that send signals to nerves, preventing seizures from happening.

Good to know: There is no evidence that Lacosam is addictive.

How to Take Lacosam

Your doctor will determine the right dose for you based on your condition, body weight, and other medications you’re taking. Always follow your doctor’s instructions carefully.

Dosage Instructions

Your doctor may start you on a low dose of 50 mg twice a day. The dose may slowly be increased up to a maximum of 300 mg twice a day until your seizures are controlled. Take Lacosam twice daily – once in the morning and once at night, at about the same time each day. Swallow tablets whole with a glass of water. It doesn’t matter if you take it before or after food.

What If You Miss a Dose?

Contact your doctor if you have missed one or more doses. Do not take a double dose to make up for the missed dose, as this may increase your chance of side effects. If you have trouble remembering doses, ask your pharmacist for helpful hints.

Important: Never take a double dose to make up for a missed dose – this increases the risk of side effects.

Available Tablet Strengths

50mg
50mg Tablet Pink, Oval • L on one side, 50 on other
100mg
100mg Tablet Dark yellow, Oval • L on one side, 100 on other
150mg
150mg Tablet Salmon, Oval • L on one side, 150 on other
200mg
200mg Tablet Blue, Oval • L on one side, 200 on other

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • dizziness or problems with balance or coordination
  • headache
  • nausea (feeling sick) or vomiting
  • feeling tired, drowsy or sleepy
  • forgetfulness
  • tremors
  • itching

Seek immediate medical attention if you experience:

  • thoughts of harming yourself
  • more frequent or more severe seizures
  • fainting or feeling lightheaded
  • heart palpitations or rapid/irregular pulse
  • shortness of breath
  • wheezing or difficulty breathing
  • swelling of face, lips, tongue or other body parts
  • rash, itching or hives on skin
  • feelings of depression
  • feeling aggressive or agitated
  • spinning sensations
  • double vision or blurred vision
  • trouble sleeping

Important Warnings

There are important safety considerations before starting Lacosam. Make sure to discuss your medical history and current medications with your doctor.

Who Should Not Take Lacosam

Do not take Lacosam if you are allergic to any of its ingredients or if you have or have had a heart condition causing an uneven heartbeat. Signs of allergic reaction include shortness of breath, wheezing, swelling of face/lips/tongue, or skin rash and hives.

Medical Conditions to Discuss

Tell your doctor if you have or have had heart problems, kidney problems, or liver problems. Also inform them about any allergies to foods, preservatives, or dyes, and all medications you’re taking, especially other antiepileptic medicines or heart medications.

Pregnancy and Breastfeeding

Tell your doctor if you are pregnant or planning to become pregnant. Lacosam may affect your developing baby, but controlling seizures during pregnancy is very important. Your doctor will weigh the risks and benefits. If you’re breastfeeding or planning to breastfeed, discuss the risks and benefits with your doctor.

Drug Interactions

Lacosam can interact with certain medications, particularly those affecting the heart. Always tell your healthcare providers about all medications you’re taking.

Contraception: Lacosam doesn’t interact with oral contraceptive pills, but other antiepileptic medicines given with Lacosam might affect contraceptive effectiveness. Your doctor may advise additional contraception methods.

  • medicines to treat heart problems
  • carbamazepine (may affect heart beat)
  • lamotrigine (may affect heart beat)
  • pregabalin (may affect heart beat)
  • barbiturates such as phenobarbitone
  • other antiepileptic medicines such as levetiracetam

Alcohol & Driving

Lacosam can affect your ability to drive safely and may interact dangerously with alcohol. Take proper precautions to ensure your safety and that of others.

Alcohol

As a safety precaution, do not take Lacosam with alcohol.

Driving and Operating Machinery

Be careful driving or operating machinery until you know how Lacosam affects you. Like other antiepileptic medicines, Lacosam may cause dizziness or drowsiness, especially at the beginning of treatment or after a dose increase. If you feel dizzy or drowsy, do not drive, operate machinery, or do anything that could be dangerous.

Storage

Keep tablets in their original pack until it’s time to take them – they won’t keep well if removed early. Store in a cool, dry place where temperature stays below 25°C. Don’t store in the bathroom, near a sink, on window sills, or in cars on hot days, as heat and dampness can destroy the medicine. Keep out of reach of children – a locked cupboard at least 1.5 meters above ground is ideal.

Overdose Information

If you think you or someone else has taken too much Lacosam, immediately call your doctor, Poisons Information Centre (13 11 26), or go to your nearest hospital emergency department, even if there are no symptoms. You may need urgent medical attention. Overdose symptoms may include feeling dizzy, drowsy, or having an upset stomach.

Frequently Asked Questions

Most antiepileptic medicines take time to work, so don’t be discouraged if you don’t feel better straight away. Your doctor may start with a low dose and slowly increase it until your seizures are controlled.

Yes, it doesn’t matter if you take Lacosam before or after food. Just swallow the tablets whole with a glass of water.

No, there is no evidence that Lacosam is addictive.

Never stop taking Lacosam suddenly as this may cause unwanted side effects or make your condition worse. Your doctor will slowly reduce your dose before you can stop taking it completely.

No, as a safety precaution, do not take Lacosam with alcohol.

Contact your doctor if you have missed one or more doses. Do not take a double dose to make up for the missed dose, as this may increase your chance of side effects.

Lacosam is not recommended for children under 4 years as its safety and effectiveness has not been established in this age group. For patients over 16 years, it can be used alone, while younger patients may use it in combination with other medicines.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.