Onglyza (Saxagliptin)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
saxagliptin
Drug Class
DPP-4 inhibitors
Used For
Lowering blood sugar levels in type 2 diabetes mellitus
How Taken
Oral tablet once daily

What Is Onglyza Used For?

Onglyza is a medication that helps manage blood sugar levels in individuals with type 2 diabetes mellitus.

Primary Uses

It is primarily used to lower blood sugar levels in patients with type 2 diabetes.

How It Works

Onglyza works by enhancing insulin levels after meals and reducing the amount of sugar produced by the body, particularly when blood sugar levels are high.

Good to know: Onglyza is not addictive.

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How to Take Onglyza

Take Onglyza as directed by your healthcare provider to effectively manage your diabetes.

Dosage Instructions

The standard dosage is one 5 mg tablet taken once daily. If you have kidney issues, your doctor may prescribe a lower dose of 2.5 mg.

What If You Miss a Dose?

If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Do not double up on doses.

Important: Never take a double dose to make up for a missed one.

Available Tablet Strengths

2.5mg
2.5mg Tablet Pale yellow, Round • 4214
5mg
5mg Tablet Pink, Round • 4215

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • Headache
  • Signs of respiratory infections (runny nose, sore throat, cough)
  • Difficulty breathing or tightness in the chest
  • Nausea or vomiting
  • Stomach pain
  • Swelling of hands or feet
  • Rash
  • Feeling anxious or depressed

Seek immediate medical attention if you experience:

  • Severe hypoglycemia
  • Allergic reactions (shortness of breath, swelling, rash)
  • Severe upper stomach pain
  • Signs of heart failure (shortness of breath, rapid weight gain, swelling of feet)

Important Warnings

There are specific warnings to consider before taking Onglyza.

Who Should Not Take Onglyza

Do not take Onglyza if you are allergic to saxagliptin or any of its ingredients, are lactose intolerant, or have a history of severe allergic reactions.

Medical Conditions to Discuss

Consult your doctor if you have type 1 diabetes, diabetic ketoacidosis, heart failure, or kidney problems.

Pregnancy and Breastfeeding

Onglyza is not recommended during pregnancy and should not be used while breastfeeding.

Drug Interactions

Certain medications may interact with Onglyza, affecting its efficacy.

  • Insulin
  • Sulfonylureas
  • Other diabetes medications

Alcohol & Driving

Be cautious with alcohol consumption and operating vehicles while on Onglyza.

Alcohol

Discuss alcohol use with your doctor as it may affect your blood sugar levels.

Driving and Operating Machinery

Be careful when driving or using machinery until you know how Onglyza affects you, as it may cause dizziness.

Storage

Store Onglyza in a cool, dry place below 30°C, away from moisture and heat. Keep it out of reach of children.

Overdose Information

If you suspect an overdose, seek immediate medical attention or contact the Poisons Information Centre at 13 11 26.

Frequently Asked Questions

Onglyza typically starts working after you take it, helping to lower blood sugar levels, especially after meals.

Yes, Onglyza can be taken with or without food.

No, Onglyza is not considered addictive.

Do not stop taking Onglyza suddenly without consulting your doctor, as it may affect your blood sugar control.

Discuss alcohol consumption with your doctor, as it can affect your blood sugar levels.

Onglyza is not known to cause weight gain; however, individual responses may vary.

Elderly patients should consult their doctor to ensure Onglyza is safe for them, especially if they have other medical conditions.

If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Do not take a double dose.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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