Nextstellis (Estetrol (As Estetrol Monohydrate) And Drospirenone)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Nextstellis Used For?
Nextstellis is a combined oral contraceptive pill that helps women prevent pregnancy.
Primary Uses
Nextstellis is primarily used to prevent pregnancy.
How It Works
Nextstellis contains estetrol, a plant-derived estrogen that mimics natural estrogen, and drospirenone, a synthetic progestin, which work together to inhibit ovulation and alter the uterine lining.
Good to know: Nextstellis is not addictive.
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How to Take Nextstellis
It is important to take Nextstellis as directed to ensure its effectiveness.
Dosage Instructions
Take one tablet every day at the same time, following the order indicated on the blister pack. Swallow both pink and white tablets whole.
What If You Miss a Dose?
If you miss one pink active tablet, take it as soon as you remember. If you miss two or more, follow specific instructions for missed doses and use backup contraception for the first seven days.
Important: Never double dose if you miss a tablet.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- acne
- headache
- irregular vaginal bleeding
- pain during periods
- weight gain
- breast tenderness
- decreased sex drive
- nausea
- mood changes
Seek immediate medical attention if you experience:
- blood clots in lungs, legs, or eyes
- heart attack
- stroke
- liver problems
- high blood pressure
Important Warnings
There are several important considerations to keep in mind when using Nextstellis.
Who Should Not Take Nextstellis
Do not use Nextstellis if you have a history of allergic reactions to its ingredients, blood clots, certain heart conditions, uncontrolled high blood pressure, severe migraines, liver problems, or if you are pregnant.
Medical Conditions to Discuss
Discuss any history of blood clotting disorders, diabetes with complications, severe liver disease, or any other significant medical conditions with your doctor before starting Nextstellis.
Pregnancy and Breastfeeding
Consult your doctor if you are pregnant or planning to become pregnant. If breastfeeding, be aware that Nextstellis may reduce milk production.
Drug Interactions
Certain medications may interact with Nextstellis and affect its effectiveness.
Grapefruit interaction: Grapefruit may affect how Nextstellis works.
- CYP inducers (e.g., carbamazepine, rifampin)
- CYP inhibitors (e.g., fluconazole, grapefruit juice)
- HIV protease inhibitors
- Certain antibiotics and herbal products like St. John's Wort
Alcohol & Driving
Nextstellis does not affect your ability to drive or operate machinery.
Alcohol
Drinking alcohol does not affect the effectiveness of Nextstellis.
Driving and Operating Machinery
Nextstellis has no influence on your ability to drive or use machines.
Storage
Store Nextstellis below 30°C and keep it out of reach of children.
Overdose Information
If you suspect an overdose of Nextstellis, seek immediate medical attention by contacting the Poisons Information Centre at 13 11 26 or visiting the nearest hospital.
Frequently Asked Questions
Nextstellis typically starts working within 7 days if taken correctly.
Yes, you can take Nextstellis with or without food.
No, Nextstellis is not addictive.
You can stop taking Nextstellis whenever you wish, but consult your doctor for a pre-pregnancy check-up if you plan to conceive.
Yes, drinking alcohol does not affect Nextstellis.
Weight gain can occur as a side effect, but it varies by individual.
Elderly patients should consult their doctor, especially if they have a history of blood clots or other serious conditions.
If you miss a dose, take it as soon as you remember and follow the instructions for missed doses.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.