Levothox (Levothyroxine Sodium)
Complete patient guide for uses, dosage, side effects, and safety information
Prescription RequiredQuick Facts
What Is Levothox Used For?
Levothox contains levothyroxine sodium, a thyroid hormone used as replacement therapy when your thyroid gland doesn’t produce enough hormones naturally.
Primary Uses
Levothox treats thyroid hormone deficiency (hypothyroidism), a condition where your thyroid gland is underactive and doesn’t produce enough levothyroxine hormone. It’s also used to treat TSH-responsive tumors of the thyroid gland.
How It Works
Levothyroxine is important for controlling your metabolism. Levothox replaces the shortage of thyroid hormones in your body, helping to restore normal thyroid function.
Good to know: It may take a few weeks for Levothox to begin working, so you may not notice changes in your symptoms immediately.
How to Take Levothox
Your doctor will calculate the right dose for you based on your individual needs. Take Levothox exactly as prescribed and follow your doctor’s instructions carefully.
Dosage Instructions
The usual starting dose for adults is 50 to 100 micrograms daily. The dose may be increased over time, with the average adult maintenance dose being 100 to 200 micrograms. Lower doses are used for elderly patients and children. Take tablets first thing in the morning on an empty stomach, at least 30 minutes and preferably 60 minutes before any food or other medications. Swallow tablets with a glass of water.
What If You Miss a Dose?
If you miss your dose and it’s almost time for your next dose, skip the missed dose and take your next dose when scheduled. Otherwise, take your dose as soon as you remember, then return to your normal schedule. Take Levothox regularly at the same time each day for best results.
Important: Never take a double dose to make up for a missed dose. Do not change your dosage unless your doctor tells you to do so.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- Nervousness
- Anxiety
- Restlessness
- Muscle weakness and cramps
- Inability to sleep
- Tremor
- Headache
- Lack of concentration
- Heat intolerance
- Excessive sweating
- Weight loss
- Hair loss
- Irritability
- Tiredness
- Diarrhea
- Stomach cramps
- Nausea
- Vomiting
- Increased appetite
- Shortness of breath
- Rapid breathing
- Irregular heartbeats
- Chest pain
- Skin rash
- Menstrual irregularities
- Decreased libido
Seek immediate medical attention if you experience:
- Severe allergic reactions (difficulty breathing, fainting, swelling of face/lips/tongue, severe skin rash)
- Signs of overdose (restlessness, vomiting, flushing, breathing difficulties, chest pain, convulsions, paralysis)
Important Warnings
Before taking Levothox, inform your doctor about all your medical conditions and medications to ensure safe use.
Who Should Not Take Levothox
Do not take Levothox if you are allergic to levothyroxine sodium, thyroid hormones, or any ingredients in the tablets. Do not take tablets if their color has changed, or if the packaging is damaged or expired.
Medical Conditions to Discuss
Tell your doctor if you have: overactive thyroid gland, adrenal gland problems, hyperthyroidism, heart problems or cardiovascular disorders, high blood pressure, diabetes, long-standing hypothyroidism, problems absorbing nutrients from the gastrointestinal tract, or allergies to other medicines, foods, preservatives or dyes.
Pregnancy and Breastfeeding
Check with your doctor if you are pregnant or planning to become pregnant. Levothyroxine levels need careful monitoring during pregnancy, and your dosage may need to be increased. Although small amounts pass into breast milk, women who are breastfeeding should continue treatment with Levothox as directed by their doctor.
Drug Interactions
Many medications can interfere with Levothox and affect how it works. Always tell your doctor about all medicines, vitamins, and supplements you’re taking.
- Anticoagulants (blood thinners like warfarin)
- Antidepressants (lithium, SSRIs, tricyclic antidepressants)
- Antivirals for HIV/AIDS (ritonavir)
- Antimalarials (chloroquine, proguanil)
- Diabetes medications (insulin)
- Beta-blockers (propranolol)
- Cholesterol medications (colestyramine)
- Corticosteroids (prednisolone, dexamethasone)
- Oral contraceptives and hormone replacement therapy
- Epilepsy medications (phenytoin, carbamazepine)
- Heart failure medications (digoxin)
- Iron supplements
- Calcium, magnesium, and aluminum supplements
- Antibiotics (rifampicin, ciprofloxacin)
- Soybean flour products
- Antacids and proton pump inhibitors
- Heart rhythm medications (amiodarone)
- Oral contrast agents for X-rays
- Thyroid medications (propylthiouracil)
- NSAIDs (pain and anti-inflammatory drugs)
- Weight loss drugs (orlistat)
Alcohol & Driving
Be cautious with activities requiring alertness until you know how Levothox affects you, and inform your doctor about alcohol consumption.
Alcohol
Tell your doctor if you drink alcohol, as this information is important for your treatment plan.
Driving and Operating Machinery
Be careful before you drive or use any machines or tools where alertness is required, until you know how Levothox affects you.
Storage
Store Levothox in the original package in a cool, dry place where the temperature stays below 25°C. Protect from light and moisture. Do not store in the bathroom, near a sink, in the car, or on window sills. Keep out of reach of children. Do not take tablets if their color has changed.
Overdose Information
If you think you have taken too much Levothox, seek urgent medical attention immediately. Overdose symptoms may include restlessness, vomiting, flushing, breathing difficulties, chest pain, convulsions, or paralysis. Contact the Poisons Information Centre (13 11 26), your doctor, or go to the nearest hospital emergency department, even if you feel fine.
Frequently Asked Questions
It may take a few weeks for Levothox to begin working. Until it begins working, you may not notice any change in your symptoms.
No, Levothox should be taken first thing in the morning on an empty stomach, at least 30 minutes and preferably 60 minutes before any food or other medications.
Do not stop using Levothox suddenly. You should continue taking it until your doctor tells you to stop, as your body needs consistent thyroid hormone replacement.
Tell your doctor if you drink alcohol, as this information is important for your treatment plan and monitoring.
If it’s almost time for your next dose, skip the missed dose. Otherwise, take it as soon as you remember, then return to your normal schedule. Never take a double dose.
Do not switch or interchange with other brands unless advised by your doctor, as different brands may have different effects.
Yes, your doctor will monitor your blood tests to make sure Levothox is working for you and may adjust your dose accordingly.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.