Colese (Mebeverine Hydrochloride)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
mebeverine hydrochloride
Drug Class
antispasmodic agent
Used For
irritable bowel syndrome symptoms including abdominal pain, cramps, bowel spasm, diarrhea and flatulence
How Taken
oral tablet, one tablet three times a day

What Is Colese Used For?

Colese contains mebeverine hydrochloride and belongs to a group of medicines called antispasmodic agents. It helps manage the uncomfortable symptoms of irritable bowel syndrome.

Primary Uses

Colese is taken to relieve the symptoms of irritable bowel syndrome, which can include abdominal pain and cramps, bowel spasm, diarrhea and flatulence.

How It Works

Colese works by relaxing the muscles in the gut, thereby relieving the symptoms of irritable bowel syndrome.

How to Take Colese

Take Colese consistently at the same times each day for the best effect. This will also help you remember when to take your medication.

Dosage Instructions

The usual dose is one tablet three times a day. Take Colese immediately before or during a meal. Swallow the tablets with a glass of water. Take at about the same time each day and continue taking until your doctor tells you to stop, even if you feel well.

What If You Miss a Dose?

If you miss your dose at the usual time, take it as soon as you remember, then go back to taking your medicine as you would normally. If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to. If you are not sure what to do, ask your doctor or pharmacist.

Important: Do not take a double dose to make up for the dose you missed. This may increase the chance of getting an unwanted side effect.

Available Tablet Strengths

135mg
135mg Tablet White, Round • sugar-coated

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • indigestion or heartburn
  • constipation
  • dizziness
  • headache
  • tiredness
  • difficulty sleeping
  • loss of appetite

Seek immediate medical attention if you experience:

  • swelling of the face, lips or tongue
  • difficulty swallowing or breathing

Important Warnings

Before taking Colese, it’s important to discuss your medical history and current medications with your doctor to ensure this medication is safe for you.

Who Should Not Take Colese

Do not take Colese if you are allergic to mebeverine hydrochloride or any of the ingredients listed. Some symptoms of an allergic reaction include skin rash, itching, shortness of breath or swelling of the face, lips or tongue, which may cause difficulty in swallowing or breathing.

Medical Conditions to Discuss

Check with your doctor if you have any of the following medical conditions: angina or other heart conditions, liver problems, kidney problems, or lactose intolerance. Also tell your doctor if you take any medicines for any other condition.

Pregnancy and Breastfeeding

Check with your doctor if you are pregnant or intend to become pregnant. Talk to your doctor if you are breastfeeding or intend to breastfeed. If you become pregnant while taking Colese, tell your doctor immediately.

Drug Interactions

Tell your doctor or pharmacist about all medicines you are taking, including prescription medications, over-the-counter medicines, vitamins and supplements.

Alcohol & Driving

Be cautious about activities that require alertness until you know how Colese affects you personally.

Driving and Operating Machinery

Be careful before you drive or use any machines or tools until you know how Colese affects you.

Storage

Keep your tablets in the pack until it is time to take them. Store Colese in a cool, dry place where the temperature stays below 25°C. Keep it where young children cannot reach it – a locked cupboard at least one-and-a-half meters above the ground is a good place to store medicines. Do not store in the bathroom, near a sink, in the car or on window sills.

Overdose Information

If you think that you have taken too much Colese, you may need urgent medical attention. You should immediately phone the Poisons Information Centre (Australia telephone 13 11 26) for advice, contact your doctor, or go to the Emergency Department at your nearest hospital. You should do this even if there are no signs of discomfort or poisoning.

Frequently Asked Questions

Take Colese immediately before or during a meal. This helps with proper absorption and reduces the chance of stomach upset.

Take the missed dose as soon as you remember, then continue with your regular schedule. If it’s almost time for your next dose, skip the missed dose. Never take a double dose to make up for a missed one.

No, do not stop taking Colese or lower the dosage without checking with your doctor first. It’s important to keep taking your medicine even if you feel well.

Remind any doctor, dentist or pharmacist you visit that you are taking Colese. If you are going to have surgery, tell the surgeon that you are taking this medication.

Keep tablets in their original pack until it’s time to take them. Store in a cool, dry place below 25°C, away from moisture, heat and sunlight. Keep out of reach of children.

The most common side effects are usually mild and include indigestion or heartburn, constipation, dizziness, headache, tiredness, difficulty sleeping, and loss of appetite. Speak to your doctor if these worry you.

Call your doctor straight away or go to the Emergency Department if you notice swelling of the face, lips or tongue, or difficulty swallowing or breathing, as these may be signs of a serious allergic reaction.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.