Cipramil (Citalopram Hydrobromide)
Complete patient guide for uses, dosage, side effects, and safety information
Prescription RequiredQuick Facts
What Is Cipramil Used For?
Cipramil contains the active ingredient citalopram hydrobromide and belongs to a group of medicines called selective serotonin reuptake inhibitors (SSRIs).
Primary Uses
Cipramil is used to treat depression. Depression is longer lasting or more severe than the normal ‘low moods’ everyone experiences from time to time due to everyday stress.
How It Works
SSRIs are thought to work by their actions on brain chemicals called amines which are involved in controlling mood. Depression is thought to be caused by a chemical imbalance in parts of the brain, and Cipramil corrects this chemical imbalance and may help relieve the symptoms of depression.
How to Take Cipramil
Your doctor will decide what dose you will receive. Take Cipramil as a single dose either in the morning or in the evening, with or without food.
Dosage Instructions
The standard dose for adults is between 20 mg and 40 mg (one to two tablets) per day. The recommended starting dose in elderly patients is 10 mg (half a tablet) per day but may be increased to a maximum of 20 mg (one tablet) per day. If you have liver problems or are taking medicines such as cimetidine and omeprazole, the recommended starting dose is 10mg (half a tablet) per day, which can be increased to a maximum of 20mg (one tablet) per day. Swallow the tablets whole with a full glass of water – do not chew them.
What If You Miss a Dose?
If you miss your dose and remember within 12 hours, take it straight away, then go back to taking it as you would normally. If it is almost time for your next dose, skip the missed dose and take your next dose when you are meant to. Do not take a double dose to make up for the missed dose.
Important: Never take a double dose to make up for a missed dose
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- decreased appetite or loss of appetite
- dry mouth
- diarrhea
- nausea
- sleeplessness
- fatigue
- sleepiness or drowsiness
- yawning
- increased sweating
- sexual disturbances
- itching
- ringing in ears
- muscle or joint pain
- flu-like symptoms
- taste disturbance
- weight changes
- constipation
- dizziness
- headache
- restlessness
Seek immediate medical attention if you experience:
- thoughts of harming yourself or suicide
- serious allergic reaction
- high fever, agitation, confusion, trembling and abrupt muscle contractions
- mania
- hallucinations
- seizures
- tremors
- movement disorders
- fast, irregular heartbeat
- chest pain
- shortness of breath
- fainting
- blurred vision
- low sodium levels in blood
Important Warnings
There are several important warnings and precautions to be aware of before taking Cipramil.
Who Should Not Take Cipramil
Do not take Cipramil if you are allergic to citalopram hydrobromide or any of the ingredients, if you have congenital long QT syndrome, if the packaging is torn or shows signs of tampering, or if you are taking MAOIs such as phenelzine, tranylcypromine, moclobemide, linezolid, or selegiline. Do not give to children or adolescents under 18 years old.
Medical Conditions to Discuss
Tell your doctor if you have: allergies to other substances, heart conditions, illnesses requiring regular blood tests, tendency to bleed or bruise easily, diabetes, kidney or liver disease, bipolar disorder, history of seizures, restlessness, raised eye pressure or glaucoma risk, epilepsy, or if you are receiving electroconvulsive therapy.
Pregnancy and Breastfeeding
Do not take Cipramil if you are pregnant unless you and your doctor have discussed the risks and benefits. When taken during pregnancy, particularly in the last three months, it may affect your newborn baby and increase the risk of persistent pulmonary hypertension of the newborn (PPHN). It may also increase the risk of heavy vaginal bleeding after birth. Do not take while breastfeeding unless risks and benefits have been discussed with your doctor, as it is excreted in breast milk.
Suicide Risk: Persons taking Cipramil may be more likely to think about killing themselves, especially when first started or when the dose is changed. Tell your doctor immediately if you have thoughts about killing yourself.
Drug Interactions
Some medicines may interfere with Cipramil and affect how it works. Tell your doctor about all medicines you are taking.
Heart Rhythm: Drugs that affect heart rhythm should be avoided while taking Cipramil. Your doctor may perform an ECG test if these medicines are necessary.
- pimozide (used to treat mental disorders)
- MAOIs such as phenelzine, tranylcypromine, moclobemide
- linezolid (antibiotic)
- selegiline (for Parkinson’s disease)
- lithium (for mood swings)
- tricyclic antidepressants (imipramine, desipramine)
- heart medications (beta-blockers, antiarrhythmics)
- sumatriptan (for migraines)
- tramadol (pain relief)
- cimetidine and omeprazole (for reflux and ulcers)
- aspirin and NSAIDs
- warfarin (blood thinner)
- St John’s Wort
- antifungal medicines (ketoconazole, fluconazole, itraconazole)
- macrolide antibiotics (erythromycin, clarithromycin)
- carbamazepine (for convulsions)
- tryptophan
- antipsychotics
- other antidepressants
Alcohol & Driving
Be careful with alcohol consumption and driving while taking Cipramil.
Alcohol
Tell your doctor if you drink alcohol. It is not advisable to drink alcohol while you are being treated for depression.
Driving and Operating Machinery
Be careful before you drive or use any machines or tools until you know how Cipramil affects you. It may cause visual disturbance (such as blurred vision), nausea, fatigue, and dizziness in some people, especially early in treatment. If you have any of these symptoms, do not drive, operate machinery, or do anything else that could be dangerous.
Storage
Store Cipramil in a cool dry place below 25°C, away from moisture, heat or sunlight. Keep your tablets in the original packaging, in a safe place, away from children. Do not store in the bathroom, near a sink, in the car, or on windowsills.
Overdose Information
If you think you have taken too much Cipramil, you may need urgent medical attention. Symptoms may include nausea, vomiting, dizziness, fast or slow heart beat, changes in heart rhythm, blood pressure changes, tremor, agitation, dilated pupils, drowsiness, sweating, bluish skin discoloration, and increased breathing rate. Convulsions or coma may occur. Immediately phone the Poisons Information Centre (13 11 26), contact your doctor, or go to the Emergency Department at your nearest hospital, even if there are no signs of discomfort.
Frequently Asked Questions
As with other medicines for treating depression, it may take a few weeks before you feel any improvement. Continue to take Cipramil even if it takes some time before you feel better, as individuals vary greatly in their response to the medication.
Yes, you can take Cipramil with or without food. Take it as a single dose either in the morning or in the evening.
Do not stop taking Cipramil suddenly. If stopped abruptly, you may experience withdrawal symptoms such as dizziness, pins and needles, sleep disturbances, anxiety, headaches, nausea, vomiting, sweating, tremor, confusion, irritability, diarrhea, visual disturbances, or irregular heartbeats. Your doctor will gradually reduce the dose over a couple of weeks.
It is not advisable to drink alcohol while you are being treated for depression. Tell your doctor if you drink alcohol.
Yes, Cipramil can be given to elderly patients over 65 years of age, but with a reduced dose. The recommended starting dose is 10 mg (half a tablet) per day, which may be increased to a maximum of 20 mg (one tablet) per day if needed.
If you remember within 12 hours, take the missed dose straight away, then continue as normal. If it’s almost time for your next dose, skip the missed dose and take your next dose when scheduled. Never take a double dose to make up for a missed dose.
The duration of treatment varies for each individual, but is usually at least 6 months. In some cases, your doctor may decide that longer treatment is necessary. Continue taking your medicine for as long as your doctor tells you, even if you begin to feel better, as stopping too soon may cause symptoms to return.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.