Hyaluronic acid has become a buzzword in the skincare and wellness industry, thanks to its incredible ability to retain moisture, improve skin elasticity, and even support joint health. But with its rising popularity, many people are asking a surprising question: Does hyaluronic acid cause weight gain? If you’ve been wondering the same, you’re not alone.
Let’s dive deep into this topic, explore the science, and uncover whether hyaluronic acid causes weight gain or if it’s just another myth floating around.
Understanding Hyaluronic Acid
Hyaluronic acid (HA) is a naturally occurring substance in the body. It’s found in high concentrations in the skin, connective tissues, and eyes, where its primary function is to retain water and keep tissues well-lubricated. Because of its ability to hold up to 1,000 times its weight in water, HA is commonly used in skincare, joint supplements, and even medical treatments like dermal fillers.
With such powerful moisture retention properties, some people assume that hyaluronic acid could contribute to weight gain. But does hyaluronic acid cause weight gain? Let’s examine the facts.

Does Hyaluronic Acid Cause Weight Gain? The Science Behind It
The short answer is: No, hyaluronic acid does not cause actual fat gain. However, it can lead to temporary water retention, which might make you feel or look slightly heavier.
1. Water Retention vs. Fat Gain
Hyaluronic acid pulls in moisture, which is why it’s so effective in keeping your skin plump and your joints lubricated. But this also means it can increase water content in your body, particularly in the skin and connective tissues. This effect may lead to slight weight fluctuations, but it’s not the same as fat gain.
- A study published in the Journalfound that hyaluronic acid injections in cosmetic procedures lead to mild swelling due to water retention, but this is temporary.
- Another study in Osteoarthritis and Cartilage noted that hyaluronic acid injections in joints improved mobility without causing any significant body weight changes.
So, does hyaluronic acid cause weight gain? It might cause slight water weight changes, but it does not contribute to fat accumulation.
2. Does Oral Hyaluronic Acid Cause Weight Gain?
Many people take hyaluronic acid supplements for joint support and skin hydration. While these supplements improve moisture retention inside the body, there’s no scientific evidence linking them to permanent weight gain.
- According to a 2021 study in Nutrients, participants who took oral hyaluronic acid for eight weeks showed increased skin hydration and reduced wrinkles, but no changes in body weight.
- Another study in Clinical Interventions in Aging confirmed that oral hyaluronic acid supplementation improves joint function with no reported effects on fat gain or metabolism.
Again, the answer to “does hyaluronic acid cause weight gain?” remains no, at least not in terms of fat gain.
3. Does Hyaluronic Acid in Skincare Cause Weight Gain?
Topical hyaluronic acid, like the ones found in serums and creams, only affects the skin. It does not enter the bloodstream or affect body weight in any way.
- A study published in Dermatologic Surgery found that hyaluronic acid improves skin hydration, elasticity, and reduces fine lines, but it does not penetrate deep enough to impact body weight.
If you’ve been worried about your skincare routine leading to weight gain, rest assured: does hyaluronic acid cause weight gain? Absolutely not when applied topically.
Temporary Side Effects of Hyaluronic Acid
Although hyaluronic acid does not cause weight gain, it may lead to temporary water retention, bloating, or swelling, especially after injections or high-dose supplements. However, these effects are usually short-lived and should not be mistaken for actual weight gain.
1. Swelling from Injections
If you receive dermal fillers containing hyaluronic acid, you might notice mild puffiness or swelling at the injection site. This can last a few days, but it’s not fat gain.
2. Water Retention from Supplements
Since HA attracts water, some people may feel mild bloating or puffiness when taking high doses. However, this is usually temporary and resolves once your body balances its hydration levels.
3. Skin Puffiness from Overuse in Skincare
Using too much hyaluronic acid in skincare can sometimes draw excess moisture to the skin’s surface, making the face look puffy. But again, this is just hydration and not actual weight gain.

Can Hyaluronic Acid Help with Weight Loss?
Interestingly, some research suggests that hyaluronic acid may even aid in weight loss due to its potential effects on joint health and mobility.
- A study in Biomed Research International found that hyaluronic acid supplementation helped improve joint flexibility, making it easier for individuals to engage in physical activity.
- Another study in Osteoarthritis Research Society International found that improved joint function through HA supplements helped participants stay active, which can indirectly support weight management.
So, while it won’t burn fat directly, hyaluronic acid can play a role in overall mobility, flexibility, and hydration, which are essential for a healthy lifestyle.
Does Hyaluronic Acid Cause Weight Gain?
To sum it up:
- Hyaluronic acid does not cause actual fat gain.
- It may cause mild water retention, but this is temporary.
- Oral hyaluronic acid does not impact metabolism or body weight.
- Topical hyaluronic acid has no effect on weight gain.
- Hyaluronic acid can even support weight loss by improving joint health and mobility.
If you’ve been asking, “does hyaluronic acid cause weight gain?” you can rest assured that the answer is no. It might lead to minor water fluctuations, but it has no impact on fat accumulation or metabolism. Instead, it offers numerous benefits for skin, joints, and overall hydration.