What Is Doryx Used For?

Doryx contains doxycycline hyclate, which belongs to a group of medicines called tetracyclines. It’s an antibiotic that works by killing or stopping the growth of bacteria and parasites.

Primary Uses

Doryx is used to treat certain types of bacterial infections, control acne, and prevent some forms of malaria (sometimes combined with another antimalarial medicine).

How It Works

It works by killing or stopping the growth of bacteria which cause infections or make acne worse. It also works against parasites that cause malaria. Tetracyclines will not work against viral infections such as colds or flu.

How to Take Doryx

Your doctor will tell you exactly how many capsules to take each day. Always follow their instructions carefully, as they may differ from general guidelines.

Dosage Instructions

For treating infections: Usually two 100 mg capsules on the first day, then one 100 mg capsule daily. For controlling acne: Usually one 50 mg capsule daily. For preventing malaria: Usually one 100 mg capsule daily, starting two days before entering the malarious area, during the visit, and for four weeks after leaving. Swallow capsules whole with a full glass of water or milk while sitting or standing upright. Take during or immediately after a meal. Stay upright for at least 30 minutes after taking to avoid throat irritation.

What If You Miss a Dose?

If you miss a dose and it’s almost time for your next dose, skip the missed dose and take your next dose when scheduled. Otherwise, take it as soon as you remember, then return to your normal schedule. If you’re unsure, ask your doctor or pharmacist.

Available Tablet Strengths

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

• Oral thrush (white, furry, sore tongue and mouth)
• Vaginal thrush (sore and itchy vagina with or without discharge)
• Rash or itching
• Nail changes
• Stomach upset or vomiting
• Mild irritation of the esophagus (food-pipe)
• Taste loss
• Ringing or other persistent noise in the ears

Important Warnings

There are several important situations where Doryx should not be used or requires special caution.

Who Should Not Take Doryx

Do not take if you’re allergic to doxycycline, other tetracyclines, or any ingredients. Do not take if you’re taking vitamin A preparations, isotretinoin, or etretinate. Do not take if you’re more than 18 weeks pregnant or breastfeeding. Do not give to children under 8 years old (or under 50 kg) unless directed by a doctor, as it may cause tooth staining and enamel loss.

Medical Conditions to Discuss

Tell your doctor if you have allergies to medicines, foods, preservatives or dyes; any other medical conditions; work outdoors or are exposed to strong sunlight (doxycycline increases sun sensitivity); or are scheduled for surgery under general anesthetic.

Pregnancy and Breastfeeding

Tetracyclines may harm your developing or breastfeeding baby, potentially causing tooth enamel loss and staining, or increased brain pressure in children. High doses may also cause liver problems in pregnant women. Check with your doctor if you’re pregnant, planning to become pregnant, or breastfeeding.

Drug Interactions

Some medicines may interfere with Doryx and affect how it works. Always tell your doctor about all medicines you’re taking.

• Vitamin A preparations
• Isotretinoin or etretinate (skin problem medicines)
• Warfarin (blood clotting prevention)
• Penicillin antibiotics
• Epilepsy medicines (phenytoin, carbamazepine, phenobarbital)
• Methoxyflurane (anesthetic)
• Acetazolamide (diuretic)
• Birth control pills (may decrease effectiveness)
• Antacids containing aluminum, calcium, or magnesium
• Bismuth salts
• Iron preparations and vitamins containing iron

Alcohol & Driving

Be cautious with activities that require alertness and discuss alcohol use with your doctor.

Alcohol

Tell your doctor if you drink alcohol. The interaction effects are not fully detailed, but it’s important for your doctor to know about your alcohol consumption.

Driving and Operating Machinery

Be careful before you drive or use any machines or tools until you know how Doryx affects you. The medication may cause dizziness or other effects that could impair your ability to operate machinery safely.

Sun Exposure

Protect your skin when in the sun, especially between 10am and 3pm. Wear protective clothing and use 30+ sunscreen. Doryx makes your skin much more sensitive to sunlight, which may cause rash, itching, redness, or severe sunburn. If your skin appears to be burning, see your doctor immediately.

Storage

Keep capsules in their original pack until it’s time to take them to protect from light. Store below 25°C in a cool, dry place away from moisture, heat, and sunlight. Don’t store in the bathroom, near a sink, in the car, or on windowsills. Keep out of reach of children.

Overdose Information

If you think you’ve taken too much Doryx, seek urgent medical attention immediately. Call the Poisons Information Centre (13 11 26), contact your doctor, or go to the nearest hospital Emergency Department, even if you don’t feel unwell. Overdose symptoms may include upset stomach or vomiting.

Frequently Asked Questions