Zerbaxa (Ceftolozane And Tazobactam)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Zerbaxa Used For?
Zerbaxa is a combination antibiotic used to treat serious bacterial infections.
Primary Uses
It is prescribed for complicated abdominal and urinary tract infections, as well as nosocomial pneumonia.
How It Works
Ceftolozane is an antibiotic that targets various bacteria, while Tazobactam enhances its effectiveness against resistant bacteria.
Good to know: Zerbaxa is not addictive.
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How to Take Zerbaxa
Zerbaxa is given through an intravenous infusion by a healthcare professional.
Dosage Instructions
The typical dose is one or two vials (1000 mg of ceftolozane and 500 mg of tazobactam) every 8 hours, depending on the infection's severity.
What If You Miss a Dose?
As Zerbaxa is administered by a healthcare professional, missed doses are unlikely. If you have concerns, consult your doctor.
Important: Never double the dose if a dose is missed.
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- Diarrhea
- Abdominal bloating
- Nausea
- Vomiting
- Rash
- Dizziness
Seek immediate medical attention if you experience:
- Severe diarrhea (C. difficile infection)
- Kidney problems
- Blood clot in a vein
- Ischemic stroke
- Decrease in blood pressure
Impulse Control Issues
No specific information about impulse control issues was mentioned.
Important Warnings
There are specific considerations and contraindications for Zerbaxa.
Who Should Not Take Zerbaxa
Do not use Zerbaxa if you are allergic to ceftolozane, tazobactam, or other beta-lactam antibiotics.
Medical Conditions to Discuss
Inform your doctor if you have a history of allergies to antibiotics, recent diarrhea, or low white blood cell counts.
Pregnancy and Breastfeeding
Discuss with your doctor if you are pregnant or breastfeeding, as they will evaluate the risks and benefits.
Elderly Patients With Dementia: Special caution is advised for elderly patients, particularly those with dementia.
Drug Interactions
Certain medications may interact with Zerbaxa.
Grapefruit interaction: There are no specific grapefruit warnings mentioned.
- Probenecid (for gout)
- Diclofenac (for pain and inflammation)
- Cimetidine (for heartburn and stomach ulcers)
Alcohol & Driving
Be cautious with alcohol consumption and driving while on Zerbaxa.
Alcohol
Consult your doctor regarding alcohol use while taking Zerbaxa.
Driving and Operating Machinery
Be careful when driving or operating machinery until you know how Zerbaxa affects you.
Temperature Regulation
No specific temperature regulation warnings were mentioned.
Storage
Store Zerbaxa in its original packaging in a refrigerator at 2 to 8 degrees Celsius.
Overdose Information
Overdose is unlikely as Zerbaxa is administered by a healthcare professional. If overdose is suspected, seek immediate medical attention.
Frequently Asked Questions
Zerbaxa typically starts to work soon after administration, but the exact time can vary based on the infection.
Zerbaxa is administered intravenously, so food intake does not affect its absorption.
No, Zerbaxa is not considered addictive.
Consult your doctor before stopping Zerbaxa to avoid complications.
It's best to discuss alcohol consumption with your doctor while on Zerbaxa.
Weight gain is not a commonly reported side effect of Zerbaxa.
Elderly patients should use Zerbaxa with caution, especially those with dementia.
As Zerbaxa is given by a healthcare professional, missed doses are unlikely. Consult your doctor if you have concerns.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.