Remicade (Infliximab)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Remicade Used For?
Remicade is a medication that helps reduce inflammation and symptoms associated with various autoimmune diseases.
Primary Uses
It is primarily used for rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, moderate to severe plaque psoriasis, Crohn's disease, and ulcerative colitis.
How It Works
Remicade works by blocking a protein called tumor necrosis factor alpha (TNFα), which is involved in inflammation.
Good to know: Remicade is not addictive.
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How to Take Remicade
Remicade is given as an infusion into a vein, typically over a period of at least 2 hours.
Dosage Instructions
For rheumatoid arthritis, the starting dose is 3 mg/kg, followed by doses at 2 and 6 weeks, then every 8 weeks. For ankylosing spondylitis and psoriatic arthritis, the starting dose is 5 mg/kg, with similar follow-up doses. For Crohn's disease and ulcerative colitis, the initial dose is also 5 mg/kg, followed by additional doses at specified intervals.
What If You Miss a Dose?
If you miss an appointment for your infusion, reschedule as soon as possible. Your doctor will determine the timing of your next dose.
Important: Never double up on doses if you miss one.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- Headache
- Nausea
- Dizziness
- Fatigue
- Rash
- Fever
Seek immediate medical attention if you experience:
- Chest pain
- Shortness of breath
- Severe fatigue
- Signs of liver problems (jaundice, dark urine)
- Nervous system issues (numbness, tingling, seizures)
Impulse Control Issues
There may be reports of new inflammatory symptoms or autoimmune disorders.
Important Warnings
There are several important considerations before starting Remicade.
Who Should Not Take Remicade
Do not use Remicade if you have had an allergic reaction to infliximab, murine proteins, or any ingredients in the medication. Also, avoid it if you have active infections or congestive heart failure.
Medical Conditions to Discuss
Discuss any history of infections, tuberculosis, hepatitis B, cancer, or nervous system disorders with your doctor.
Pregnancy and Breastfeeding
Remicade is not recommended during pregnancy, and adequate contraception is advised during treatment and for at least 6 months after. It can pass into breast milk, so consult your doctor about breastfeeding.
Drug Interactions
Certain medications may interact with Remicade.
Grapefruit interaction: No grapefruit warnings mentioned.
- Anakinra
- Abatacept
- Live vaccines
Alcohol & Driving
While Remicade is unlikely to cause drowsiness, caution is advised when driving or operating machinery.
Alcohol
No specific alcohol warnings mentioned.
Driving and Operating Machinery
If you feel tired, avoid driving or using heavy machinery.
Temperature Regulation
No temperature regulation warnings mentioned.
Storage
Store Remicade as directed by your healthcare provider.
Overdose Information
Overdose is unlikely as Remicade is administered under medical supervision. If you suspect an overdose, seek immediate medical attention.
Frequently Asked Questions
The effects of Remicade may vary, and some patients may notice improvements within a few weeks.
Remicade is administered as an infusion and does not have specific food interactions.
No, Remicade is not considered addictive.
Consult your doctor before stopping Remicade, as sudden discontinuation may worsen your condition.
There are no specific warnings against alcohol use, but moderation is advised.
Weight gain is not a commonly reported side effect of Remicade.
Elderly patients should discuss their overall health and any specific concerns with their doctor before starting Remicade.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.