Provera (Medroxyprogesterone Acetate)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
medroxyprogesterone acetate
Drug Class
progestogen
Used For
treating endometriosis, secondary amenorrhea, abnormal uterine bleeding, certain cancers, and menopausal symptoms
How Taken
oral tablet, taken at the same time each day

What Is Provera Used For?

Provera is a medication that contains the active ingredient medroxyprogesterone acetate, which is similar to the natural hormone progesterone. It is used to manage various conditions related to hormonal imbalances.

Primary Uses

Provera is used to treat endometriosis, secondary amenorrhea (absence of menstrual periods not due to pregnancy), abnormal uterine bleeding, certain types of cancer (including breast, kidney, and endometrial cancers), and to relieve menopausal symptoms in women with an intact uterus.

How It Works

Provera works by mimicking the effects of progesterone, helping to regulate the menstrual cycle and manage conditions related to hormonal imbalances.

Good to know: Provera is not considered addictive.

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How to Take Provera

It is important to take Provera exactly as prescribed by your doctor to achieve the best results.

Dosage Instructions

Your doctor will determine the appropriate dosage based on your specific condition. Provera should be taken at the lowest effective dose, either daily or in cycles as directed.

What If You Miss a Dose?

If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Do not take a double dose.

Important: Never double dose to make up for a missed dose.

Available Tablet Strengths

2.5mg
2.5mg Tablet Orange, Round • U64
5mg
5mg Tablet Blue, Round • 286
10mg
10mg Tablet White, Round • UPJOHN 50
100mg
100mg Tablet White, Scored • U467
200mg
200mg Tablet White, Scored • U320
250mg
250mg Tablet White, Scored • U403
500mg
500mg Tablet White, Capsule-shaped • UPJOHN 717

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • dizziness
  • increased heart rate
  • mood changes
  • sleepiness
  • skin conditions
  • changes in menstrual periods
  • changes in vaginal secretions
  • breast changes
  • changes in sex drive
  • weight changes
  • fluid retention

Seek immediate medical attention if you experience:

  • sudden vision loss
  • severe headaches
  • chest pain or shortness of breath
  • swelling in arms or legs
  • seizures
  • allergic reactions

Impulse Control Issues

There is no specific mention of impulse control issues related to Provera.

Important Warnings

There are several important considerations to keep in mind when using Provera.

Who Should Not Take Provera

Do not use Provera if you have a history of allergic reactions to medroxyprogesterone acetate or any of its ingredients, have certain medical conditions such as a history of stroke, blood clots, severe liver disease, or breast cancer, or if you are pregnant.

Medical Conditions to Discuss

Discuss any history of heart problems, kidney issues, migraines, epilepsy, asthma, diabetes, depression, or bone diseases with your doctor before starting Provera.

Pregnancy and Breastfeeding

Provera should not be taken if you are pregnant or suspect you may be pregnant, as it may harm the developing baby. Consult your doctor if you are breastfeeding or plan to breastfeed.

Elderly Patients With Dementia: Elderly patients, especially those with dementia, may be at increased risk of side effects.

Drug Interactions

Certain medications may interact with Provera and affect its effectiveness.

Grapefruit interaction: No specific grapefruit interaction mentioned.

  • aminoglutethine (used for breast cancer treatment)

Alcohol & Driving

Be cautious when consuming alcohol or driving while taking Provera, as it may cause dizziness or affect your vision.

Alcohol

There is no specific information on how Provera interacts with alcohol, but it is advisable to discuss alcohol consumption with your doctor.

Driving and Operating Machinery

Avoid driving or operating machinery until you know how Provera affects you, as it may cause dizziness or sleepiness.

Storage

Store Provera in a cool, dry place below 30°C and keep it in its original packaging until you are ready to take it.

Overdose Information

If you suspect an overdose of Provera, seek immediate medical attention. Contact your doctor or the Poisons Information Centre at 13 11 26.

Frequently Asked Questions

The time it takes for Provera to work can vary depending on the condition being treated. Consult your doctor for specific timelines.

Provera can be taken with a full glass of water, but specific instructions regarding food should be discussed with your doctor.

Provera is not considered addictive.

Do not stop taking Provera without consulting your doctor, as this may affect your treatment.

Discuss alcohol consumption with your doctor, as there is no specific information on interactions.

Weight changes can occur while taking Provera, so monitor your weight and discuss any concerns with your doctor.

Elderly patients may be at increased risk of side effects, so it is important to consult with a doctor.

If you miss a dose, take it as soon as you remember, but do not double dose.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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