Pentasa Sachets (Mesalazine)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Pentasa Sachets Used For?
Pentasa Sachets contain mesalazine, which is used to manage inflammation in the bowel associated with Crohn's disease and ulcerative colitis.
Primary Uses
Pentasa is primarily used to treat Crohn's disease and ulcerative colitis, conditions that cause inflammation, ulcers, and sores in the bowel, leading to symptoms like bleeding, stomach pain, and diarrhea.
How It Works
Mesalazine works by reducing inflammation in the bowel, similar to how aspirin functions.
Good to know: Pentasa is not considered addictive.
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How to Take Pentasa Sachets
It's important to take Pentasa as prescribed by your doctor to effectively manage your condition.
Dosage Instructions
For ulcerative colitis, take up to 4 g once daily or in divided doses during flare-ups, and up to 2 g once daily for maintenance. For Crohn's disease, take up to 4 g daily in divided doses for both active disease and maintenance.
What If You Miss a Dose?
If you miss a dose, skip it and take your next dose at the scheduled time. Do not double the dose.
Important: Never double dose to make up for a missed dose.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- headache
- diarrhea
- abdominal pain
- nausea
- vomiting
- flatulence
- mild skin rash
Seek immediate medical attention if you experience:
- chest pain
- irregular heartbeat
- shortness of breath
- severe upper stomach pain
- unusual bleeding
- numbness or tingling in limbs
- severe diarrhea or bloody stools
- yellowing of skin or eyes
- changes in urine output
Important Warnings
There are important considerations to keep in mind before taking Pentasa.
Who Should Not Take Pentasa Sachets
Do not take Pentasa if you are allergic to mesalazine, sulfasalazine, or aspirin-like medications, have severe kidney or liver problems, or if the packaging is damaged.
Medical Conditions to Discuss
Inform your doctor if you have a history of kidney or liver issues, bleeding disorders, asthma, or if you are taking other medications.
Pregnancy and Breastfeeding
Consult your doctor if you are pregnant, plan to become pregnant, or are breastfeeding, as Pentasa should be used cautiously during these times.
Drug Interactions
Certain medications may interact with Pentasa, so it's important to inform your healthcare provider about all medications you are taking.
- Anticoagulants (e.g., warfarin)
- Sulphonylureas (e.g., glibenclamide, glipizide)
- Methotrexate
- Glucocorticoids (e.g., prednisolone)
- Probenecid or sulfinpyrazone
- Spironolactone or furosemide
- Rifampicin
- Azathioprine
- Mercaptopurine
- Tioguanine
Alcohol & Driving
While taking Pentasa, it is advisable to be cautious with alcohol consumption and driving.
Alcohol
Consult your doctor regarding alcohol use while on Pentasa.
Driving and Operating Machinery
Pentasa is not expected to impair your ability to drive or operate machinery.
Storage
Store Pentasa in a cool, dry place below 25°C, away from moisture and heat. Keep it out of reach of children.
Overdose Information
If you suspect an overdose of Pentasa, seek immediate medical attention. Contact the Poisons Information Centre at 13 11 26 or go to the nearest hospital.
Frequently Asked Questions
The time it takes for Pentasa to work can vary by individual, but it is important to continue taking it as prescribed for the best results.
You can take Pentasa with or without food.
No, Pentasa is not considered addictive.
Do not stop taking Pentasa suddenly without consulting your doctor, as it may worsen your condition.
Consult your doctor regarding alcohol consumption while taking Pentasa.
Weight gain is not listed as a common side effect of Pentasa.
Elderly patients should discuss their health conditions with their doctor before taking Pentasa.
If you miss a dose, skip it and take your next dose at the scheduled time. Do not double the dose.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.