Mylotarg (Gemtuzumab Ozogamicin)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
gemtuzumab ozogamicin
Drug Class
antineoplastic agents
Used For
treatment of acute myeloid leukaemia (AML) in patients aged 15 and above
How Taken
administered via intravenous infusion over 2 hours

What Is Mylotarg Used For?

Mylotarg is a medication used to treat acute myeloid leukaemia (AML) in patients who are 15 years and older.

Primary Uses

Mylotarg is primarily used for the treatment of acute myeloid leukaemia (AML), a type of cancer affecting the blood and bone marrow.

How It Works

Mylotarg works by stopping the abnormal growth of cancer cells and destroying them.

Good to know: Mylotarg is not considered addictive.

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How to Take Mylotarg

Mylotarg is given in cycles under the supervision of a healthcare professional.

Dosage Instructions

The dosage of Mylotarg is calculated based on your height and weight, and it may vary depending on your condition and response to previous treatments. It is administered in cycles, typically one to three cycles, with specific dosing on designated days.

What If You Miss a Dose?

If you miss a scheduled dose of Mylotarg, contact your healthcare provider as soon as possible to reschedule.

Important: Never double dose if you miss a treatment.

Available Tablet Strengths

5mg
5mg Tablet Blue, Round • A-007
10mg
10mg Tablet Pink, Rectangular • A-008
15mg
15mg Tablet Yellow, Round • A-009
20mg
20mg Tablet White, Round • A-010
30mg
30mg Tablet Pink, Round • A-011

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • Nausea
  • Vomiting
  • Fatigue
  • Headache
  • Skin rash or itching
  • Changes in appetite

Seek immediate medical attention if you experience:

  • Venoocclusive liver disease
  • Infusion-related reactions (fever, chills, rash)
  • Shortness of breath or wheezing
  • Frequent bruising or nosebleeds
  • Signs of infection (fever, chills)

Impulse Control Issues

There is no specific mention of impulse control issues related to Mylotarg.

Important Warnings

There are significant warnings associated with Mylotarg that patients should be aware of.

Who Should Not Take Mylotarg

Do not use Mylotarg if you have had an allergic reaction to gemtuzumab ozogamicin or any of its ingredients.

Medical Conditions to Discuss

Discuss any liver problems, kidney issues, infections, bleeding disorders, or anemia with your doctor before starting treatment.

Pregnancy and Breastfeeding

Avoid becoming pregnant or fathering a child while receiving Mylotarg. It is not recommended during pregnancy due to potential harm to the unborn baby. Breastfeeding is also not advised during treatment and for at least one month after the last dose.

Elderly Patients With Dementia: Special caution is advised for elderly patients, particularly those with dementia.

Drug Interactions

Certain medications may interact with Mylotarg and affect its effectiveness.

Grapefruit interaction: Grapefruit may interact with Mylotarg; consult your doctor for advice.

  • Other cancer treatments
  • Blood thinners
  • Medications affecting liver function

Alcohol & Driving

Caution is advised regarding alcohol consumption and operating vehicles while on Mylotarg.

Alcohol

Consult your doctor about alcohol use while taking Mylotarg.

Driving and Operating Machinery

Be cautious when driving or using machinery until you know how Mylotarg affects you, as it may cause fatigue.

Temperature Regulation

No specific temperature regulation warnings are mentioned.

Storage

Mylotarg must be stored in a refrigerator and protected from light until it is administered by a healthcare professional.

Overdose Information

Overdose is unlikely as Mylotarg is administered under professional supervision. In case of an overdose, healthcare providers will monitor for side effects.

Frequently Asked Questions

The effectiveness of Mylotarg can vary by individual, and your doctor will monitor your response to treatment.

There are no specific instructions regarding food interactions with Mylotarg.

Mylotarg is not considered addictive.

Do not stop using Mylotarg suddenly without consulting your doctor, as it may affect your treatment.

Consult your doctor regarding alcohol consumption while on Mylotarg.

Weight gain is not specifically mentioned as a side effect of Mylotarg.

Elderly patients should use Mylotarg with caution, especially those with dementia.

Contact your healthcare provider as soon as possible to reschedule if you miss a dose.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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