Metalyse 25 mg (Tenecteplase)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Metalyse 25 mg Used For?
Metalyse is a medication used in adults to treat strokes caused by blood clots in the brain's arteries.
Primary Uses
It is primarily used for treating acute ischaemic stroke.
How It Works
Metalyse works by dissolving blood clots that obstruct normal blood flow.
Good to know: Metalyse is not addictive.
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How to Take Metalyse 25 mg
Metalyse is given as an injection by a healthcare professional as soon as possible after stroke symptoms begin.
Dosage Instructions
The recommended dose for treating acute ischaemic stroke is based on body weight, ranging from 15 mg to 25 mg, administered as a single injection over 5 to 10 seconds.
What If You Miss a Dose?
This medication is administered in a clinical setting, so missed doses are not applicable.
Important: Only one injection of Metalyse should be given.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- Bleeding more easily than usual
- Nausea
- Vomiting
Seek immediate medical attention if you experience:
- Bleeding or blood clot in the brain
- Severe allergic reactions
- Low blood pressure
Important Warnings
There are several important warnings to consider before receiving Metalyse.
Who Should Not Take Metalyse 25 mg
Do not take Metalyse if you have a known allergy to tenecteplase or any of its ingredients, have had a stroke without significant neurological impairment, or have certain bleeding disorders.
Medical Conditions to Discuss
Discuss with your doctor if you have a history of bleeding disorders, high blood pressure, liver disease, or any recent major injuries or surgeries.
Pregnancy and Breastfeeding
Inform your doctor if you are pregnant or breastfeeding, as they can help weigh the risks and benefits.
Elderly Patients With Dementia: Elderly patients, especially those over 80, may have an increased risk of side effects.
Drug Interactions
Certain medications may interact with Metalyse and affect its effectiveness.
- Antiplatelet medications (e.g., aspirin)
- Anticoagulants (e.g., heparin, warfarin)
- Angiotensin Converting Enzyme (ACE) inhibitors
Alcohol & Driving
Avoid alcohol while taking Metalyse, as it may increase the risk of side effects.
Alcohol
Alcohol can increase the risk of bleeding.
Driving and Operating Machinery
Be cautious when driving or operating machinery until you know how Metalyse affects you.
Storage
Store Metalyse in a cool, dry place away from direct sunlight and out of reach of children.
Overdose Information
An overdose is unlikely as Metalyse is administered under medical supervision. If overdose occurs, bleeding may be a symptom, and treatment will be adjusted accordingly.
Frequently Asked Questions
Metalyse is most effective when administered as soon as possible after the onset of stroke symptoms.
Metalyse is given as an injection, so food intake does not affect its administration.
No, Metalyse is not considered addictive.
Since Metalyse is administered in a clinical setting, sudden discontinuation is not applicable.
It is advisable to avoid alcohol while taking Metalyse due to the increased risk of bleeding.
Weight gain is not a known side effect of Metalyse.
Elderly patients should be monitored closely due to an increased risk of side effects.
Missed doses are not applicable as Metalyse is given in a medical setting.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.