Lonsurf (Trifluridine And Tipiracil)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Lonsurf Used For?
Lonsurf is a medication designed to treat certain types of cancer by inhibiting the growth and spread of cancer cells.
Primary Uses
Lonsurf is primarily used for adults with colorectal cancer and gastric cancer, especially when the cancer has metastasized or when other treatments have failed.
How It Works
Lonsurf contains trifluridine, which halts the growth of cancer cells, and tipiracil, which prevents trifluridine from being broken down, allowing it to remain effective longer.
Good to know: Lonsurf is not considered addictive.
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How to Take Lonsurf
Follow your doctor's instructions carefully when taking Lonsurf.
Dosage Instructions
Typically, Lonsurf is prescribed for 10 days during the first two weeks, followed by a two-week break. This cycle is repeated as directed by your doctor.
What If You Miss a Dose?
If you miss a dose, do not take it later. Record the missed dose and inform your doctor or pharmacist immediately.
Important: Never double the dose to make up for a missed one.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- Nausea
- Decreased appetite
- Fatigue
- Rash
- Hair loss
Seek immediate medical attention if you experience:
- Neutropenia (low white blood cell count)
- Anemia (low red blood cell count)
- Thrombocytopenia (low platelet count)
- Severe gastrointestinal issues (vomiting, diarrhea)
- Signs of infection (fever, chills)
Important Warnings
There are important considerations to keep in mind before using Lonsurf.
Who Should Not Take Lonsurf
Do not use Lonsurf if you have a known allergy to trifluridine, tipiracil, or any other ingredients in the medication.
Medical Conditions to Discuss
Discuss any kidney or liver problems with your doctor, as Lonsurf may not be suitable for you.
Pregnancy and Breastfeeding
Lonsurf is not recommended during pregnancy or breastfeeding. Effective contraception is advised during treatment and for six months after stopping.
Drug Interactions
Certain medications may interact with Lonsurf, affecting its efficacy.
- Zidovudine (HIV treatment)
Alcohol & Driving
Be cautious with alcohol consumption and operating machinery while on Lonsurf.
Alcohol
Consult your doctor about alcohol use while taking Lonsurf.
Driving and Operating Machinery
Do not drive or operate heavy machinery until you know how Lonsurf affects you.
Storage
Store Lonsurf in a cool, dry place away from moisture and sunlight, out of reach of children.
Overdose Information
If you suspect an overdose, seek immediate medical attention or contact the Poisons Information Centre at 13 11 26.
Frequently Asked Questions
The effects of Lonsurf can vary, and your doctor will monitor your response to treatment.
It is recommended to take Lonsurf immediately after meals.
No, Lonsurf is not considered addictive.
Do not stop taking Lonsurf without consulting your doctor, as it may affect your treatment.
Consult your doctor regarding alcohol consumption while on Lonsurf.
Weight changes can occur; discuss any concerns with your doctor.
Elderly patients should consult their doctor for personalized advice regarding Lonsurf.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.