Kanjinti (Trastuzumab (Rch))

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
trastuzumab (rch)
Drug Class
monoclonal antibodies (anti-neoplastic agents)
Used For
treatment of HER2 positive breast and gastric cancer
How Taken
intravenous infusion, frequency varies

What Is Kanjinti Used For?

KANJINTI is a biosimilar medicine that contains trastuzumab, used primarily for treating certain types of cancer.

Primary Uses

KANJINTI is used to treat breast cancer and gastric cancer in patients whose tumors test positive for the HER2 protein.

How It Works

KANJINTI binds to the HER2 protein found in excess on some cancer cells, inhibiting their growth and spread.

Good to know: KANJINTI is not addictive.

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How to Take Kanjinti

KANJINTI is administered by a healthcare professional through an intravenous infusion.

Dosage Instructions

The first infusion is typically given over 90 minutes. If well tolerated, subsequent infusions may be shortened to 30 minutes. For breast cancer, it can be given weekly or every three weeks, while for gastric cancer, it is administered every three weeks with chemotherapy.

What If You Miss a Dose?

If you miss an appointment for KANJINTI, reschedule as soon as possible. Your doctor will determine the next dose timing.

Important: Do not double dose if you miss an appointment.

Available Tablet Strengths

150 mg
150 mg Tablet White to pale yellow, Powder
420 mg
420 mg Tablet White to pale yellow, Powder

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • nausea
  • fatigue
  • rash
  • fever
  • chills

Seek immediate medical attention if you experience:

  • allergic reactions (swelling, difficulty breathing)
  • heart problems (shortness of breath, irregular heartbeat)
  • severe infections

Important Warnings

There are several important considerations before starting KANJINTI.

Who Should Not Take Kanjinti

Do not use KANJINTI if you have had an allergic reaction to it, any of its ingredients, or any protein from Chinese hamster origin. It's also contraindicated in patients with non-metastatic breast cancer and a left ventricular ejection fraction (LVEF) of less than 45%.

Medical Conditions to Discuss

Inform your doctor if you have a history of heart disease, breathing issues, or have been treated with anthracyclines, as these can increase the risk of heart problems.

Pregnancy and Breastfeeding

KANJINTI may harm an unborn baby. Effective contraception is advised during treatment and for 7 months after. Breastfeeding should be discontinued during treatment and not resumed until 7 months post-treatment.

Drug Interactions

Certain medications may interact with KANJINTI, increasing the risk of lung problems.

  • gemcitabine
  • vinorelbine
  • taxanes
  • radiation therapy

Alcohol & Driving

Be cautious with alcohol and driving while on KANJINTI, as it may affect your ability to perform these activities.

Alcohol

Consult your doctor about alcohol consumption while on KANJINTI.

Driving and Operating Machinery

Avoid driving or operating machinery until you know how KANJINTI affects you.

Storage

KANJINTI should be stored in a refrigerator at temperatures between 2°C and 8°C.

Overdose Information

Overdose is unlikely as KANJINTI is administered under medical supervision. If you experience side effects, contact your doctor immediately.

Frequently Asked Questions

The effects of KANJINTI can vary, and your doctor will monitor your response to treatment.

KANJINTI is given as an intravenous infusion, so food intake does not affect its administration.

No, KANJINTI is not considered addictive.

Do not stop KANJINTI without consulting your doctor, as it may affect your treatment.

Consult your doctor regarding alcohol consumption while on KANJINTI.

Weight changes are not specifically mentioned, but report any significant changes to your doctor.

Elderly patients should discuss their overall health with their doctor before starting KANJINTI.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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