Estrofem (Estradiol Hemihydrate)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Estrofem Used For?
Estrofem is a hormone replacement therapy that helps alleviate symptoms caused by low estrogen levels in women, particularly those who have undergone a hysterectomy or are experiencing menopause.
Primary Uses
Estrofem is primarily used to treat symptoms of estrogen deficiency, such as hot flushes, night sweats, sleep disturbances, vaginal dryness, urinary issues, headaches, mood swings, lack of concentration, and fatigue.
How It Works
Estrofem works by replenishing estrogen levels in the body, helping to alleviate menopausal symptoms.
Good to know: Estrofem is not considered addictive.
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How to Take Estrofem
Take Estrofem exactly as prescribed by your doctor. It is important to follow the dosage instructions carefully.
Dosage Instructions
The typical dosage is one tablet taken daily at the same time. Estrofem is available in a 28-day calendar pack, and you should continue taking it without interruption after finishing a pack.
What If You Miss a Dose?
If you miss a dose, take it as soon as you remember if it's within 12 hours. If more than 12 hours have passed, skip the missed dose and continue with your regular schedule. Do not take a double dose.
Important: Never double dose to make up for a missed dose.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- breast tenderness or pain
- vaginal bleeding or spotting
- abdominal pain
- nausea
- headaches
- mood changes
- weight changes
Seek immediate medical attention if you experience:
- blood clots
- severe allergic reactions
- unexpected vaginal bleeding
- lumps in the breast
- sudden severe headaches
- vision problems
Impulse Control Issues
There is a potential risk of impulse control issues, including gambling or spending problems.
Important Warnings
There are several important warnings to consider before using Estrofem.
Who Should Not Take Estrofem
Do not use Estrofem if you are pregnant, breastfeeding, have a history of breast cancer, endometrial cancer, unexplained vaginal bleeding, blood clots, liver disease, or are allergic to any of its ingredients.
Medical Conditions to Discuss
Discuss with your doctor if you have a history of fibroids, endometriosis, high blood pressure, diabetes, migraines, or any blood clotting disorders.
Pregnancy and Breastfeeding
Estrofem should not be used during pregnancy or while breastfeeding.
Elderly Patients With Dementia: Caution is advised for elderly patients, especially those with dementia.
Drug Interactions
Certain medications may interact with Estrofem and affect its effectiveness.
Grapefruit interaction: Consult your doctor if you consume grapefruit, as it may affect how Estrofem works.
- barbiturates
- phenytoin
- carbamazepine
- rifampicin
- rifabutin
- nevirapine
- efavirenz
- ritonavir
- nelfinavir
- St. John's Wort
Alcohol & Driving
Be cautious with alcohol consumption and operating machinery while taking Estrofem.
Alcohol
There is no specific information on the effects of alcohol while taking Estrofem, but it's advisable to discuss alcohol consumption with your doctor.
Driving and Operating Machinery
There is no specific information on driving or operating machinery while taking Estrofem, but use caution until you know how it affects you.
Storage
Store Estrofem in a cool, dry place below 25°C, away from moisture and sunlight. Keep it out of reach of children.
Overdose Information
If you suspect an overdose of Estrofem, seek medical attention immediately. Contact the Poisons Information Centre at 13 11 26 or go to the nearest hospital.
Frequently Asked Questions
Estrofem typically begins to alleviate symptoms of low estrogen within a few weeks of starting treatment.
You can take Estrofem with or without food, but it's best to take it at the same time each day.
No, Estrofem is not considered addictive.
Do not stop taking Estrofem suddenly without consulting your doctor, as it may lead to a return of symptoms.
It's advisable to discuss alcohol consumption with your doctor while taking Estrofem.
Weight changes can occur while taking Estrofem; consult your doctor if you have concerns.
Elderly patients should use Estrofem with caution, especially those with dementia.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.