Calquence tablets (Acalabrutinib Maleate Monohydrate)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Calquence tablets Used For?
Calquence tablets are designed to combat certain types of blood cancers by targeting specific proteins that aid in cancer cell growth.
Primary Uses
Calquence is primarily used to treat Mantle Cell Lymphoma (MCL) and Chronic Lymphocytic Leukaemia (CLL)/Small Lymphocytic Lymphoma (SLL).
How It Works
Calquence works by inhibiting Bruton tyrosine kinase (BTK), which may help reduce the number of cancer cells and slow their spread.
Good to know: Calquence is not considered addictive.
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How to Take Calquence tablets
It is important to follow your doctor's instructions when taking Calquence tablets to ensure the best results.
Dosage Instructions
The typical dose is one 100 mg tablet taken twice daily, approximately 12 hours apart. Swallow the tablet whole with water.
What If You Miss a Dose?
If you miss a dose by more than 3 hours, skip the missed dose and take your next dose at the scheduled time. Do not double up on doses.
Important: Never take a double dose to make up for a missed one.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- Bleeding and bruising
- Nausea and vomiting
- Diarrhea
- Headache
- Dizziness
- Fatigue
Seek immediate medical attention if you experience:
- Signs of serious bleeding (e.g., blood in stools or urine)
- Signs of infection (e.g., fever, chills)
- Heart problems (e.g., chest discomfort, shortness of breath)
- New cancers, including skin cancer
Important Warnings
There are several important safety considerations to keep in mind before using Calquence tablets.
Who Should Not Take Calquence tablets
Do not take Calquence if you are pregnant, breastfeeding, or allergic to acalabrutinib or any of its ingredients.
Medical Conditions to Discuss
Inform your doctor if you have any bleeding disorders, infections, liver problems, heart rhythm issues, or if you are planning surgery.
Pregnancy and Breastfeeding
Calquence may harm an unborn baby. Effective contraception is advised during treatment and for at least one week after the last dose. Do not breastfeed while taking Calquence.
Drug Interactions
Certain medications may interact with Calquence and affect its efficacy.
- Medicines for heart rhythm control (e.g., amiodarone, diltiazem, verapamil)
- Antibiotics (e.g., clarithromycin, erythromycin)
- Fungal infection treatments (e.g., fluconazole, itraconazole)
- HIV medications (e.g., ritonavir, cobicistat)
- Seizure medications (e.g., carbamazepine, phenytoin)
- St. John’s wort
- Methotrexate
- Blood sugar control medications (e.g., metformin)
Alcohol & Driving
Be cautious with alcohol consumption and operating machinery while on Calquence.
Alcohol
Consult your doctor about alcohol use while taking Calquence.
Driving and Operating Machinery
Be careful when driving or using machinery until you know how Calquence affects you, as it may cause dizziness.
Storage
Store Calquence tablets in a cool, dry place below 30°C. Keep them away from moisture and sunlight.
Overdose Information
If you suspect an overdose, seek immediate medical attention. Contact the Poisons Information Centre at 13 11 26 or go to the nearest hospital.
Frequently Asked Questions
The time it takes for Calquence to show effects can vary by individual, and your doctor can provide more specific information.
You can take Calquence with or without food.
No, Calquence is not considered addictive.
Do not stop taking Calquence without consulting your doctor, as this may affect your treatment.
Consult your doctor regarding alcohol consumption while on Calquence.
Elderly patients should discuss their health conditions with their doctor before taking Calquence.
If you miss a dose by more than 3 hours, skip it and take your next dose at the scheduled time.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.