Perindo (Perindopril Erbumine)
Complete patient guide for uses, dosage, side effects, and safety information
Prescription RequiredQuick Facts
What Is Perindo Used For?
Perindo contains perindopril erbumine, which belongs to a group of medicines called ACE inhibitors. It’s available only with a doctor’s prescription and helps treat several heart and blood pressure conditions.
Primary Uses
Perindo is used to lower high blood pressure (hypertension), treat heart failure when the heart muscle cannot pump blood strongly enough, and reduce risks in patients with coronary artery disease including heart attacks. High blood pressure usually has no symptoms, but if untreated can lead to stroke, heart disease and kidney failure.
How It Works
As an ACE inhibitor, Perindo helps lower blood pressure and reduces the workload on your heart. For heart failure patients, it can improve your ability to perform daily activities, help you breathe more easily, feel less tired, and reduce swelling.
Good to know: You may feel fine with high blood pressure and have no symptoms, but Perindo helps prevent serious complications like stroke and heart disease.
How to Take Perindo
Your doctor will decide and adjust the dose of Perindo you need. Take your tablets exactly as prescribed to get the full benefits of treatment.
Dosage Instructions
The usual dose is 2mg (PERINDO 2), 4mg (PERINDO 4) or 8mg (PERINDO 8) once daily for high blood pressure and coronary artery disease, or 2mg to 4mg once daily for heart failure. Swallow your tablet(s) with water, preferably in the morning before a meal. For elderly patients, the starting dose should always be 2mg.
What If You Miss a Dose?
If it’s almost time for your next dose, skip the missed dose and take your next dose when scheduled. Otherwise, take it as soon as you remember, then return to your normal schedule.
Important: Never take a double dose to make up for a missed dose. Continue taking Perindo for as long as your doctor tells you – it controls your condition but doesn’t cure it.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- Dry, irritating cough
- Headache, dizziness, pins and needles
- Changes in heart rhythm or rate
- Feeling tired or weak
- Ringing in ears, vision changes
- Low blood pressure, flushing
- Nausea, vomiting, taste changes, stomach problems
- Muscle cramps
- Skin rash, itching
Seek immediate medical attention if you experience:
- Angioedema: swelling of face, lips, mouth, tongue or throat causing difficulty swallowing or breathing
- Fast and irregular heartbeat
- Purple spots with blisters on arms, legs, neck or ears (Stevens-Johnson Syndrome)
- Difficulty breathing
- Severe skin reactions, blisters, or allergic reactions
- Signs of low sodium: concentrated dark urine, nausea, muscle cramps, confusion, fits
Important Warnings
There are important situations where Perindo should not be used, and conditions that require special monitoring. Always inform your doctor about your complete medical history.
Who Should Not Take Perindo
Do not take Perindo if you are allergic to perindopril or other ACE inhibitors, have experienced angioedema (swelling of face, tongue, lips or throat) with previous ACE inhibitor treatment, are pregnant or breastfeeding, undergo certain blood treatments like dialysis with specific membranes, are treated with aliskiren and have diabetes or kidney problems, have kidney artery stenosis, or are taking sacubitril/valsartan.
Medical Conditions to Discuss
Tell your doctor if you have kidney disease, liver disease, aortic stenosis, diabetes, heart disease, systemic lupus erythematous, are of African origin (higher angioedema risk and less effectiveness), have abnormal aldosterone levels, or problems with salt balance. Also inform them about recent diarrhea/vomiting, dehydration, salt-restricted diet, or if you’re undergoing desensitization treatment or surgery.
Pregnancy and Breastfeeding
Do not take Perindo if you are pregnant, trying to become pregnant, or breastfeeding. Tell your doctor immediately if you become pregnant while taking Perindo as it may cause serious harm to your baby.
Elderly Patients: Perindo can generally be used safely by elderly people, but reduced kidney function is common in elderly patients, so the starting dose should always be 2mg.
Drug Interactions
Perindo may interact with many medications, potentially changing how well it works or increasing side effects. Always inform your healthcare providers that you’re taking Perindo.
- Other blood pressure medications including angiotensin receptor blockers and aliskiren
- Diuretics (water tablets)
- Antibiotics and infection treatments
- Anti-inflammatory drugs including high-dose aspirin and ibuprofen
- Mood medications like lithium, tricyclic antidepressants, antipsychotics
- Potassium supplements and salt substitutes containing potassium
- Immunosuppressants
- Diabetes medications (tablets and insulin)
- Blood-thinning medications like heparin
- mTOR inhibitors, sacubitril/valsartan, and gliptins (increase angioedema risk)
Alcohol & Driving
Perindo can affect your ability to drive or operate machinery, and you should take precautions with physical activity and hydration.
Alcohol
The source does not specifically mention alcohol interactions, but consult your doctor about alcohol consumption while taking Perindo.
Driving and Operating Machinery
Take care when driving or operating machinery until you know how Perindo affects you. Dizziness or weakness due to low blood pressure may occur. If you experience these symptoms, do not drive or operate machinery.
Temperature Regulation
Make sure you drink enough water during exercise and hot weather, especially if you sweat a lot. This helps avoid dizziness or light-headedness caused by sudden drops in blood pressure.
Storage
Keep your tablets in the original pack until it’s time to take them. Store in a cool, dry place below 30°C. Don’t store in bathrooms, near sinks, in cars, or on windowsills. Keep the container tightly closed and out of reach of children. Heat and dampness can destroy the medicine.
Overdose Information
Taking too much Perindo may cause dangerously low blood pressure, making you feel dizzy or faint. Other possible effects include nausea, cramps, sleepiness, confusion, kidney problems, and salt/water imbalances. If overdose is suspected, immediately call your doctor, Poisons Information Centre (13 11 26 in Australia), or go to the nearest hospital emergency department, even if there are no symptoms. Lying down with legs elevated can help with low blood pressure symptoms.
Frequently Asked Questions
The source doesn’t specify exact timing, but Perindo helps control blood pressure, heart failure, and coronary artery disease. Your doctor will monitor your response and may adjust your dose as needed.
Yes, you should swallow your tablet with water, preferably in the morning before a meal.
Don’t stop taking Perindo without checking with your doctor, even if you’re feeling better. Perindo controls your condition but doesn’t cure it, so you need to continue taking it as long as your doctor tells you.
Yes, Perindo can generally be used safely by elderly people. However, since reduced kidney function is often found in elderly patients, the starting dose should always be 2mg.
If it’s almost time for your next dose, skip the missed dose and take your next dose when scheduled. Otherwise, take it as soon as you remember, then return to your normal schedule. Never take a double dose.
No, Perindo is not recommended for children.
Tell your doctor straight away if you have excessive vomiting or diarrhea while taking Perindo, as this can affect how the medication works and may require medical attention.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.