Kesimpta (Ofatumumab)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Kesimpta Used For?
Kesimpta is a medication that contains ofatumumab, which is designed to treat adults with relapsing forms of multiple sclerosis.
Primary Uses
Kesimpta is primarily used for managing relapsing forms of multiple sclerosis in adults.
How It Works
Ofatumumab targets and eliminates B-cells, which are part of the immune system, helping to reduce the frequency of relapses and slow the progression of multiple sclerosis.
Good to know: Kesimpta is not addictive.
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How to Take Kesimpta
Kesimpta is administered through subcutaneous injections, and it is important to follow the prescribed schedule.
Dosage Instructions
Inject 20mg under the skin on weeks 0, 1, and 2. There is no injection on week 3. Starting from week 4, continue with monthly injections of 20mg.
What If You Miss a Dose?
If you miss a dose, inject it as soon as possible without waiting for the next scheduled dose. Do not double the dose.
Important: Never double the dose to make up for a missed one.
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- Upper chest infections (sore throat, runny nose)
- Local injection site reactions (redness, pain, itching, swelling)
- General injection site reactions (fever, headache, muscle pain, chills, tiredness)
Seek immediate medical attention if you experience:
- Worsening multiple sclerosis symptoms (muscle weakness, stiffness, spasms, vision changes)
- Allergic reactions (rash, hives, trouble breathing, swelling of face or throat)
- New or worsening tiredness, dark urine, yellowing of skin
Important Warnings
There are several important considerations to keep in mind before using Kesimpta.
Who Should Not Take Kesimpta
Do not use Kesimpta if you are allergic to ofatumumab or any of its ingredients.
Medical Conditions to Discuss
Discuss any history of hepatitis B, liver issues, severe infections, or a weakened immune system with your doctor.
Pregnancy and Breastfeeding
Avoid becoming pregnant while using Kesimpta and for 6 months after stopping. Consult your doctor if you are pregnant or breastfeeding.
Drug Interactions
Certain medications may affect how Kesimpta works.
- Ocrelizumab
- Cladribine
- Fingolimod
- Natalizumab
- Teriflunomide
- Mitoxantrone
- Dimethyl fumarate
- Vaccines
Alcohol & Driving
There are specific considerations regarding alcohol consumption and driving while using Kesimpta.
Alcohol
No known interactions between Kesimpta and alcohol.
Driving and Operating Machinery
It is unclear how Kesimpta affects your ability to drive or operate machinery, so exercise caution.
Storage
Store Kesimpta in the refrigerator between 2°C and 8°C. Do not freeze. Keep out of reach of children.
Overdose Information
If you suspect an overdose, seek immediate medical attention. Contact the Poisons Information Centre at 13 11 26 or go to the nearest hospital.
Frequently Asked Questions
The exact time for Kesimpta to take effect can vary; consult your doctor for specific information.
There are no specific dietary restrictions mentioned for Kesimpta.
Kesimpta is not considered addictive.
Do not stop using Kesimpta suddenly without consulting your doctor, as this may lead to worsening symptoms.
There are no known interactions between Kesimpta and alcohol.
Weight gain is not listed as a side effect of Kesimpta.
Consult your doctor regarding the safety of Kesimpta for elderly patients.
Inject the missed dose as soon as possible without waiting for the next scheduled dose. Do not double the dose.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.