Janumet XR (Sitagliptin And Metformin)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
Sitagliptin and Metformin
Drug Class
DPP-4 inhibitors and Biguanides
Used For
Lowering blood sugar levels in adults with type 2 diabetes mellitus
How Taken
Oral tablet once daily with a meal

What Is Janumet XR Used For?

Janumet XR is a medication that combines sitagliptin and metformin to help manage blood sugar levels in adults diagnosed with type 2 diabetes mellitus.

Primary Uses

It is primarily used to lower blood sugar levels in adults with type 2 diabetes, alongside diet and exercise.

How It Works

Sitagliptin is a DPP-4 inhibitor that increases insulin production and decreases glucose production, while metformin improves insulin sensitivity.

Good to know: Janumet XR is not considered addictive.

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How to Take Janumet XR

Janumet XR should be taken as prescribed by your doctor, typically once a day with a meal to minimize stomach upset.

Dosage Instructions

Your doctor will determine the appropriate dosage, which is usually taken as one tablet daily.

What If You Miss a Dose?

If you miss a dose, take it as soon as you remember. If it's close to your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Important: Do not double dose to make up for a missed dose.

Available Tablet Strengths

50mg/500mg
50mg/500mg Tablet Light blue, Oval • 78
50mg/1000mg
50mg/1000mg Tablet Light green, Oval • 80
100mg/1000mg
100mg/1000mg Tablet Blue, Oval • 81

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • Signs of respiratory infections such as runny nose, sore throat, cough, flu-like symptoms
  • Stomach discomfort, vomiting, diarrhea, or constipation
  • Muscle aches or joint pain
  • Itching or blisters

Seek immediate medical attention if you experience:

  • Allergic reactions including rash, hives, and swelling of the face, lips, tongue, or throat
  • Severe stomach pain with nausea and vomiting
  • Kidney problems that may require dialysis
  • Low blood sugar when combined with sulfonylureas or insulin

Impulse Control Issues

There is no mention of impulse control issues related to Janumet XR.

Important Warnings

It is crucial to be aware of certain warnings before taking Janumet XR.

Who Should Not Take Janumet XR

Do not take Janumet XR if you are allergic to sitagliptin, metformin, or any of its ingredients.

Medical Conditions to Discuss

Discuss with your doctor if you have type 1 diabetes, severe kidney issues, liver or heart problems, or if you drink excessive alcohol.

Pregnancy and Breastfeeding

Janumet XR is not recommended during pregnancy or while breastfeeding.

Elderly Patients With Dementia: Elderly patients, especially those with dementia, should use caution when taking this medication.

Drug Interactions

Certain medications may interact with Janumet XR, affecting its efficacy.

Grapefruit interaction: No grapefruit interaction is mentioned in the source.

  • Sulfonylureas
  • Insulin

Alcohol & Driving

It is important to be cautious with alcohol consumption and driving while taking Janumet XR.

Alcohol

Inform your doctor if you consume alcohol.

Driving and Operating Machinery

There is no information suggesting that Janumet XR affects your ability to drive or operate machinery.

Temperature Regulation

No specific temperature regulation warnings are mentioned.

Storage

Store Janumet XR in a cool, dry place away from moisture, heat, and sunlight. Keep it in its original bottle until it's time to take it.

Overdose Information

If you suspect an overdose of Janumet XR, seek immediate medical attention. Symptoms may include nausea, vomiting, stomach pain, and difficulty breathing.

Frequently Asked Questions

Janumet XR begins to work by lowering blood sugar levels after taking it as prescribed.

Yes, it is recommended to take Janumet XR with a meal to reduce stomach upset.

No, Janumet XR is not considered addictive.

Do not stop taking Janumet XR without consulting your doctor, as it may affect your blood sugar control.

Inform your doctor if you drink alcohol, as it may affect your treatment.

There is no specific mention of weight gain associated with Janumet XR.

Elderly patients should use caution and consult their doctor before taking Janumet XR.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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