Dovato (Dolutegravir And Lamivudine)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Dovato Used For?
Dovato is a medication that combines dolutegravir and lamivudine to help manage HIV infection.
Primary Uses
Dovato is used to treat HIV infection in adults and children over the age of 12.
How It Works
Dovato slows down the production of HIV in the body, helping to protect the immune system.
Good to know: Dovato is not addictive.
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How to Take Dovato
It is important to take Dovato as directed by your healthcare provider.
Dosage Instructions
The usual dosage is one tablet taken once daily, swallowed whole with a glass of water.
What If You Miss a Dose?
If you miss a dose and it's within 4 hours of your next dose, skip the missed dose. Otherwise, take it as soon as you remember, but do not double the dose.
Important: Never take a double dose to make up for a missed dose.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- headache
- nausea
- vomiting
- abdominal pain
- diarrhea
- fatigue
- dizziness
- rash
- itching
- joint pain
- muscle pain
Seek immediate medical attention if you experience:
- lactic acidosis
- hepatitis
- allergic reactions (swelling, difficulty breathing)
- suicidal thoughts
- anemia
- pancreatitis
- muscle tissue breakdown
- peripheral neuropathy
Impulse Control Issues
Some patients may experience impulse control issues, including suicidal thoughts, particularly if they have a history of mental health problems.
Important Warnings
There are several important considerations to keep in mind while using Dovato.
Who Should Not Take Dovato
Do not use Dovato if you are allergic to dolutegravir, lamivudine, or any of its ingredients. Avoid it if you are taking dofetilide, pilsicainide, or fampridine.
Medical Conditions to Discuss
Inform your doctor if you have liver disease, kidney disease, or a history of hepatitis B.
Pregnancy and Breastfeeding
Consult your doctor if you are pregnant or breastfeeding, as Dovato can pass into breast milk.
Elderly Patients With Dementia: Caution is advised for elderly patients, especially those with dementia.
Drug Interactions
Certain medications can interact with Dovato, affecting its efficacy.
Grapefruit interaction: Grapefruit can affect how Dovato works.
- dofetilide
- pilsicainide
- fampridine
- emtricitabine
- antacids
- calcium, magnesium, and iron supplements
- etravirine
- efavirenz
- nevirapine
- tipranavir/ritonavir
- rifampicin
- trimethoprim/sulfamethoxazole
- phenytoin
- phenobarbital
- carbamazepine
- St. John's wort
Alcohol & Driving
Be cautious with alcohol consumption and operating machinery while taking Dovato.
Alcohol
Consult your doctor regarding alcohol consumption while on Dovato.
Driving and Operating Machinery
Dovato may cause dizziness or tiredness; exercise caution when driving or using machinery.
Storage
Store Dovato below 30°C in a cool, dry place, away from moisture and sunlight.
Overdose Information
If you suspect an overdose, seek immediate medical attention. Contact the Poisons Information Centre at 13 11 26 or go to the nearest hospital.
Frequently Asked Questions
Dovato begins to work by slowing down the production of HIV in the body, but the exact time may vary by individual.
Yes, Dovato can be taken with or without food.
No, Dovato is not considered addictive.
Do not stop taking Dovato suddenly without consulting your doctor, as it may worsen your condition.
Consult your doctor regarding alcohol consumption while on Dovato.
Weight gain has been reported as a side effect in some patients; discuss any concerns with your doctor.
Elderly patients should use Dovato with caution, especially those with dementia.
If you miss a dose, take it as soon as you remember unless it's close to your next dose; do not double up.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.