Atgam (Equine Antithymocyte Immunoglobulin)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
equine antithymocyte immunoglobulin
Drug Class
Immunosuppressant
Used For
Preventing kidney transplant rejection
How Taken
Administered by slow infusion into a vein over at least 4 hours

What Is Atgam Used For?

Atgam is an immunosuppressant that helps control the immune response to foreign proteins, specifically after a kidney transplant.

Primary Uses

Atgam is primarily used to prevent the rejection of a transplanted kidney.

How It Works

It contains equine antithymocyte immunoglobulin, which helps modulate the immune system's response.

Good to know: Atgam is not considered addictive.

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How to Take Atgam

Atgam is administered by a healthcare professional through an intravenous infusion.

Dosage Instructions

The dosage will be determined by your doctor, typically following skin testing.

What If You Miss a Dose?

Atgam is given under medical supervision, making missed doses unlikely.

Important: Never double dose if a treatment is missed.

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • Fever
  • Chills
  • Sore mouth or throat
  • Feeling unwell or tired
  • Cough
  • Hiccups
  • Nosebleed
  • Pain, swelling, or redness at injection site
  • Sweating
  • Stomach pain
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Skin rash
  • Headache
  • Dizziness

Seek immediate medical attention if you experience:

  • Difficulty breathing
  • Swelling of the face, lips, or tongue
  • Anaphylaxis
  • Fast or slow heart rate
  • Severe muscle spasms
  • Convulsions
  • Signs of blood disorders
  • Unexplained bruising or bleeding
  • Dark urine or blood in urine

Important Warnings

There are several important considerations before using Atgam.

Who Should Not Take Atgam

Do not use Atgam if you have a known allergy to equine antithymocyte immunoglobulin or other horse proteins.

Medical Conditions to Discuss

Discuss any pre-existing conditions, especially those related to blood or immune system issues.

Pregnancy and Breastfeeding

Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as risks and benefits need to be evaluated.

Elderly Patients With Dementia: Special caution is advised for elderly patients, especially those with dementia.

Drug Interactions

Certain medications may interact with Atgam.

Alcohol & Driving

Caution is advised regarding alcohol consumption and driving while on Atgam.

Alcohol

No specific information is available regarding alcohol interactions.

Driving and Operating Machinery

Atgam may cause dizziness or confusion, affecting your ability to drive or operate machinery.

Storage

Atgam is stored in a hospital setting, and unused products are disposed of by medical staff.

Overdose Information

Overdose is unlikely as Atgam is administered under medical supervision.

Frequently Asked Questions

Atgam's effects are typically seen shortly after administration, but individual responses may vary.

There is no specific information regarding food interactions with Atgam.

No, Atgam is not considered addictive.

Consult your doctor before stopping Atgam, as it may affect your immune response.

There is no specific information available regarding alcohol consumption with Atgam.

Weight gain is not listed as a side effect of Atgam.

Elderly patients should use Atgam with caution, especially those with dementia.

Missed doses are unlikely as Atgam is administered in a controlled medical setting.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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