Arazil (Donepezil Hydrochloride)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
donepezil hydrochloride
Drug Class
acetylcholinesterase inhibitor
Used For
treatment of mild, moderate, and severe Alzheimer's disease
How Taken
oral tablet, usually taken once daily

What Is Arazil Used For?

Arazil is a medication that helps manage symptoms of Alzheimer's disease, which is a form of dementia. It is not a cure but may improve memory and cognitive function.

Primary Uses

Arazil is primarily used to treat mild, moderate, and severe Alzheimer's disease.

How It Works

Arazil works by increasing levels of acetylcholine, a chemical in the brain that is important for memory and thinking.

Good to know: Arazil is not considered addictive.

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How to Take Arazil

It is important to follow your doctor's instructions when taking Arazil to ensure its effectiveness.

Dosage Instructions

The usual starting dose is one 5 mg tablet taken daily. After one month, your doctor may increase the dose to 10 mg daily based on your response.

What If You Miss a Dose?

If you forget to take a tablet, take it the next day at the usual time. Do not take a double dose to make up for a missed one.

Important: Never double the dose if you miss one.

Available Tablet Strengths

5mg
5mg Tablet White, Round • DL over 5
10mg
10mg Tablet White, Round • DL over 10

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • heartburn
  • indigestion
  • stomach pain
  • headache
  • dizziness
  • difficulty sleeping
  • unusual tiredness
  • nausea
  • diarrhea
  • vomiting
  • loss of appetite
  • weight loss
  • bruising
  • muscle cramps
  • joint pain
  • tingling or numbness in hands or feet
  • depression
  • unusual dreams
  • agitation
  • increased urination

Seek immediate medical attention if you experience:

  • hallucinations
  • tremors
  • shuffling walk
  • severe stomach pain with nausea and fever
  • changes in heart activity
  • fast irregular heartbeat
  • fainting

Impulse Control Issues

Monitor for any changes in behavior, including increased impulsivity or aggression.

Important Warnings

There are several important considerations to keep in mind before using Arazil.

Who Should Not Take Arazil

Do not use Arazil if you are allergic to donepezil hydrochloride or any of its ingredients.

Medical Conditions to Discuss

Discuss with your doctor if you have heart problems, seizures, asthma, or a history of aggressive behavior.

Pregnancy and Breastfeeding

Consult your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.

Elderly Patients With Dementia: Elderly patients with dementia should be monitored closely while taking Arazil.

Drug Interactions

Certain medications may interact with Arazil and affect its effectiveness.

Grapefruit interaction: Grapefruit may affect how Arazil works.

  • medicines for other types of dementia
  • muscle relaxants
  • anti-fungal medications like ketoconazole
  • antibiotics such as clarithromycin and erythromycin
  • medications for heart rhythm problems like amiodarone
  • medications for depression including citalopram and fluoxetine
  • anti-psychotic medications

Alcohol & Driving

Be cautious with alcohol consumption and operating vehicles while on Arazil.

Alcohol

Avoid alcohol as it may increase side effects.

Driving and Operating Machinery

Arazil may cause fatigue and dizziness; do not drive or operate machinery until you know how it affects you.

Storage

Store Arazil in its blister pack in a cool, dry place below 25°C, away from moisture and heat.

Overdose Information

If you suspect an overdose, seek immediate medical attention or contact the Poisons Information Centre at 13 11 26.

Frequently Asked Questions

It may take several weeks to notice improvements in memory and thinking.

Arazil can be taken with or without food.

No, Arazil is not considered addictive.

Do not stop taking Arazil without consulting your doctor, as it may worsen your condition.

It is advisable to avoid alcohol while taking Arazil.

Weight loss is a common side effect, not weight gain.

Elderly patients should be monitored closely while taking Arazil.

Take the missed dose the next day at the usual time; do not double the dose.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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