Zavicefta (Ceftazidime And Avibactam)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Zavicefta Used For?
Zavicefta is an antibiotic that combines ceftazidime and avibactam, used to treat serious infections.
Primary Uses
It treats serious infections of the stomach, urinary tract, kidneys, and certain lung infections.
How It Works
It works by inhibiting bacterial cell wall synthesis and protecting ceftazidime from degradation by certain enzymes.
Good to know: Zavicefta is not considered addictive.
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How to Take Zavicefta
Zavicefta is given by a healthcare professional, and the dosage will depend on various factors.
Dosage Instructions
The doctor will determine the appropriate dose based on the type of infection, age, body weight (for children), and kidney function.
What If You Miss a Dose?
If a dose is missed, contact your healthcare provider for guidance.
Important: Never double the dose if you miss one; consult your doctor.
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- Stomach pain
- Diarrhea
- Nausea or vomiting
- Changes in taste or a metallic taste
- Itchy skin
- Skin rash or hives
- Dizziness
- Headache
- Fever
- White, furry layer on the tongue
- Unusual vaginal discharge
Seek immediate medical attention if you experience:
- Swelling of the face, lips, mouth, or throat causing difficulty in swallowing or breathing
- Shortness of breath or breathing difficulties
- Severe abdominal pain
- Persistent diarrhea or stools containing blood or mucus
- Severe skin reactions (e.g., painful red areas, large blisters)
- Yellowing of the skin and eyes (jaundice)
Important Warnings
There are specific warnings associated with Zavicefta usage.
Who Should Not Take Zavicefta
Do not use if allergic to ceftazidime, avibactam, or any ingredients in Zavicefta.
Medical Conditions to Discuss
Inform your doctor if you have kidney problems, anemia, or are on a controlled sodium diet.
Pregnancy and Breastfeeding
Consult your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.
Elderly Patients With Dementia: Use with caution in elderly patients, especially those with dementia.
Drug Interactions
Certain medications may interact with Zavicefta.
Grapefruit interaction: No grapefruit interaction mentioned.
- Probenecid
- Aminoglycosides (e.g., gentamicin, tobramycin)
- Cephalosporins (e.g., cefazolin, ceftazidime)
- Chloramphenicol
- Diuretics (e.g., frusemide)
Alcohol & Driving
Precautions should be taken regarding alcohol consumption and operating vehicles.
Alcohol
No specific information available regarding alcohol consumption.
Driving and Operating Machinery
Zavicefta may affect your ability to drive or operate machinery; use caution.
Temperature Regulation
No temperature regulation warnings mentioned.
Storage
Store Zavicefta in its original carton below 30°C and keep it away from moisture and sunlight.
Overdose Information
In case of overdose, seek immediate medical attention. Contact the Poisons Information Centre at 13 11 26 or visit the nearest hospital.
Frequently Asked Questions
The time it takes to work can vary depending on the infection being treated.
Consult your doctor for specific advice regarding food interactions.
No, Zavicefta is not considered addictive.
Consult your doctor before stopping any medication.
There is no specific information available regarding alcohol consumption.
Weight gain is not listed as a side effect.
Elderly patients should use Zavicefta with caution, especially those with dementia.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.