Fasenra Pen (Benralizumab)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
benralizumab
Drug Class
monoclonal antibody
Used For
Eosinophilic asthma in patients aged 12 and over, and eosinophilic granulomatosis with polyangiitis (EGPA) in adults aged 18 and over.
How Taken
Subcutaneous injection every 4 weeks for the first 3 doses, then every 8 weeks for asthma; every 4 weeks for EGPA.

What Is Fasenra Pen Used For?

Fasenra Pen is a medication that contains benralizumab, which is used to manage specific types of asthma and a condition known as eosinophilic granulomatosis with polyangiitis (EGPA).

Primary Uses

Fasenra Pen is primarily used to treat eosinophilic asthma in adults and adolescents aged 12 years and older, and EGPA in adults aged 18 years and older.

How It Works

Benralizumab works by binding to the interleukin-5 receptor on eosinophils, reducing their levels in the blood and tissues, which helps to decrease inflammation associated with asthma and EGPA.

Good to know: Fasenra Pen is not addictive.

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How to Take Fasenra Pen

Fasenra Pen is administered as a subcutaneous injection, which can be given by a healthcare professional or by the patient/caregiver after proper training.

Dosage Instructions

For asthma, the recommended dosage is 30 mg (one injection) every 4 weeks for the first 3 doses, followed by one injection every 8 weeks. For EGPA, the dosage is 30 mg every 4 weeks.

What If You Miss a Dose?

If you miss a dose, contact your doctor, nurse, or pharmacist as soon as possible for guidance on rescheduling your injection.

Important: Never double the dose if you miss one; consult your healthcare provider for instructions.

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • headache
  • sore throat
  • fever or high temperature
  • injection site reactions (pain, redness, itching, swelling)

Seek immediate medical attention if you experience:

  • allergic reactions (rash, itching, swelling of face/lips/tongue, difficulty breathing, dizziness)

Important Warnings

There are important considerations to keep in mind before using Fasenra Pen.

Who Should Not Take Fasenra Pen

Do not use Fasenra Pen if you have a known allergy to benralizumab or any of its ingredients. It should not be used for treating acute asthma attacks.

Medical Conditions to Discuss

Inform your doctor if you have a history of allergic reactions to benralizumab, infections caused by parasites, or if you are currently taking other medications.

Pregnancy and Breastfeeding

Consult your doctor if you are pregnant, plan to become pregnant, or are breastfeeding, as the effects on unborn babies or breast milk are not fully known.

Drug Interactions

Certain medications may interact with Fasenra Pen, affecting its effectiveness.

Alcohol & Driving

Fasenra Pen is not expected to impair your ability to drive or operate machinery.

Alcohol

There are no specific warnings regarding alcohol consumption while using Fasenra Pen.

Driving and Operating Machinery

Fasenra Pen is not expected to affect your driving abilities.

Storage

Store Fasenra Pen in the refrigerator at a temperature between 2°C and 8°C. It should not be frozen or exposed to heat. It can be kept at room temperature (up to 25°C) for a maximum of 14 days.

Overdose Information

If you suspect an overdose of Fasenra Pen, seek immediate medical attention. Contact your doctor or go to the nearest hospital.

Frequently Asked Questions

The effects of Fasenra Pen can vary, but it is designed to help control asthma and EGPA symptoms over time with regular use.

There are no specific dietary restrictions mentioned for taking Fasenra Pen.

No, Fasenra Pen is not considered addictive.

Do not stop taking Fasenra Pen without consulting your doctor, as it may lead to a return of symptoms.

There are no specific warnings against alcohol consumption while using Fasenra Pen.

Weight gain is not listed as a common side effect of Fasenra Pen.

There is no specific information regarding the safety of Fasenra Pen in elderly patients, but consult your doctor for personalized advice.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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