DBL Methotrexate Injection (Methotrexate)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
methotrexate
Drug Class
antineoplastic/cytotoxic
Used For
certain cancers, severe psoriasis, rheumatoid arthritis
How Taken
injection, frequency determined by doctor

What Is DBL Methotrexate Injection Used For?

DBL Methotrexate Injection contains methotrexate, which is used to treat specific types of cancers, severe psoriasis, and rheumatoid arthritis when other treatments have failed.

Primary Uses

It is primarily used for treating certain cancers, severe psoriasis, and rheumatoid arthritis.

How It Works

Methotrexate works by blocking an enzyme necessary for cell survival, which interferes with the rapid growth of cells in psoriasis and cancer. In rheumatoid arthritis, it reduces immune system overactivity, alleviating pain and swelling.

Good to know: DBL Methotrexate Injection is not addictive.

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How to Take DBL Methotrexate Injection

DBL Methotrexate Injection is administered by a healthcare professional based on individual needs.

Dosage Instructions

The dosage depends on the condition being treated, the patient's medical history, age, size, and kidney and liver function. Methotrexate is typically administered once a week.

What If You Miss a Dose?

If a dose is missed, contact your healthcare provider for instructions.

Important: Never double the dose if you miss one.

Available Tablet Strengths

5mg
5mg Tablet Blue, Round • A-007
10mg
10mg Tablet Pink, Rectangular • A-008
15mg
15mg Tablet Yellow, Round • A-009
20mg
20mg Tablet White, Round • A-010
30mg
30mg Tablet Pink, Round • A-011

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • Nausea
  • Stomach pain
  • Fatigue
  • Dizziness
  • Sore mouth
  • Blurred vision

Seek immediate medical attention if you experience:

  • Severe allergic reactions
  • Severe skin rash
  • Persistent cough
  • Breathing difficulties
  • Severe infections
  • Signs of liver damage

Impulse Control Issues

Methotrexate may affect impulse control, leading to issues such as gambling or spending.

Important Warnings

There are several important safety considerations when using DBL Methotrexate Injection.

Who Should Not Take DBL Methotrexate Injection

Do not use if you are allergic to methotrexate or any ingredients, have severe kidney problems, lowered immunity, are breastfeeding, or are pregnant.

Medical Conditions to Discuss

Discuss with your doctor if you have kidney or liver issues, lung problems, diabetes, or blood disorders.

Pregnancy and Breastfeeding

Methotrexate can cause birth defects and miscarriages. Both partners must use reliable contraception during treatment and for a specified period afterward. Breastfeeding is not recommended while using this medication.

Elderly Patients With Dementia: Special care is required for elderly patients and those with dementia.

Drug Interactions

Certain medications can interact with DBL Methotrexate Injection, affecting its efficacy.

Grapefruit interaction: Avoid grapefruit as it may interact with DBL Methotrexate Injection.

  • Some antibiotics
  • Sulphonylureas (diabetes medications)
  • Diuretics
  • Phenytoin (epilepsy treatment)
  • Ciclosporin and azathioprine (transplant medications)
  • NSAIDs (non-steroidal anti-inflammatory drugs)
  • Allopurinol and probenecid (gout medications)
  • Theophylline (asthma treatment)
  • Cholestyramine (cholesterol medication)
  • Amiodarone (heart disorder treatment)
  • Retinoids (skin condition treatments)

Alcohol & Driving

Precautions regarding alcohol consumption and driving while using DBL Methotrexate Injection.

Alcohol

Do not consume alcohol while taking this medication, as it can increase side effects and risk of liver damage.

Driving and Operating Machinery

Be cautious when driving or operating machinery, as DBL Methotrexate Injection can cause dizziness and drowsiness.

Storage

DBL Methotrexate Injection should be stored in a pharmacy or hospital setting.

Overdose Information

In case of an overdose, seek immediate medical attention. Symptoms may include severe side effects like blood in stools, severe infections, or mouth ulcers.

Frequently Asked Questions

The time it takes to see results can vary based on the condition being treated and individual response.

Consult your healthcare provider for specific advice regarding food interactions.

No, DBL Methotrexate Injection is not considered addictive.

Consult your doctor before stopping the medication, as it may lead to a worsening of your condition.

No, alcohol should be avoided as it can increase side effects and cause liver damage.

Weight gain is not commonly reported, but discuss any concerns with your doctor.

Elderly patients may require special care and monitoring while using this medication.

Contact your healthcare provider for instructions if you miss a dose.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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